Lipoamido-PEG2-alcohol Chemical Properties

Boiling point:

546.5±35.0 °C(Predicted)

Density 

1.163±0.06 g/cm3(Predicted)

pka

14.36±0.10(Predicted)

Lipoamido-PEG2-alcohol Usage And Synthesis

Description

Lipoamido-PEG2-alcohol is a linker with lipoamide moiety and a reactive alcohol group. The alcohol group can react to further derivatize the compound. The hydrophilic PEG sparcer increases the compound's water solublility in aqueous media.

Uses

Lipoamido-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Lipoamido-PEG2-alcohol(1674386-82-3)Related Product Information

• Lipoamido-PEG2-CH2CH2COOH
• Lipoamide-PEG2-Mal
• Lipoamido-PEG4-alcohol
• Lipoamido-PEG3-Azide
• Lipoamido-PEG4-acid
• alpha-lipoic acid-NHS
• Thiol-PEG3-acid
• Lipoamide-PEG3-Mal
• Thiol-dPEG4-t-boc-N-amido
• Lipoamido-PEG3-alcohol
• Tetrazine-PEG5-NHS ester
• Tetrazine-PEG5-COOH