2-(3-(4-hydroxyphenyl)propanamido)benzoic acid Chemical Properties

Boiling point:

590.0±40.0 °C(Predicted)

Density 

1.354±0.06 g/cm3(Predicted)

vapor pressure 

0Pa at 20℃

pka

3.47±0.10(Predicted)

Water Solubility 

86.5mg/L at 20℃

InChI

InChI=1S/C16H15NO4/c18-12-8-5-11(6-9-12)7-10-15(19)17-14-4-2-1-3-13(14)16(20)21/h1-6,8-9,18H,7,10H2,(H,17,19)(H,20,21)

InChIKey

DLFOKZQWYFNKCL-UHFFFAOYSA-N

SMILES

C(O)(=O)C1=CC=CC=C1NC(=O)CCC1=CC=C(O)C=C1

LogP

3.05 at 20℃

2-(3-(4-hydroxyphenyl)propanamido)benzoic acid Usage And Synthesis

Treatment of Allergy

2-(3-(4-hydroxyphenyl)propanamido)benzoic acid, also called hydroxyphenyl propamidobenzoic acid, is a good anti-irritant ingredient effectively reduces skin itching. It is derived from the active ingredient of oat (Avena Sativa), also known as dihydro oat acyl anthranilic acid, oat avenanthramides or oat amide. Oat amide is an antioxidant substance unique in oat and has the highest content in the aleurone layer. Oat amide is used in bath product additives to relieve dry skin symptoms and skin itching.
2-(3-(4-hydroxyphenyl) propanamido) benzoic acid is a kind of efficient ingredients in anti-irritant and inflammation reduction. It is an antihistamine which can effectively reduces itching and redness. Moreover, this drug has a wide range of applications, such as a remarkable effect on skin care, hair care, body care and scalp care.

Safety

Some experts have studied the functional role of hydroxyphenyl propamidobenzoic acid in animals. The mice were fed in 2 groups. One is normal and the other added hydroxyphenyl propamidobenzoic acid at a dose of 0.1 g/kg, the purpose of which is to see the ability of this substance to regulate the tissue oxidation and antioxidant balance in the mice. In addition, 50 days after feeding the mice, the two groups of mice were divided into the exercise group and the non-exercise group to study the effect of hydroxyphenyl propamidobenzoic acid on the oxidation induced by exercise in the internal organs of mice.

Uses

2-(3-(4-hydroxyphenyl)propanamido)benzoic acid can be used as a raw material for cosmetics, It works as a skin soothing agent thanks to its triple anti-irritant benefits: reduces redness, inflammation and itch PLUS has anti-oxidant efficacy.

Flammability and Explosibility

Non flammable

2-(3-(4-hydroxyphenyl)propanamido)benzoic acid(697235-49-7)Related Product Information

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