SU 5214
SU 5214 Basic information
- Product Name:
- SU 5214
- Synonyms:
-
- SU 5214;SU-5214;SU5214
- SU 5214
- SU4949
- 2H-Indol-2-one, 1,3-dihydro-3-[(2-methoxyphenyl)methylene]-
- FLK-1,SU5214,Vascular endothelial growth factor receptor,VEGFR,SU4949,inhibit,VEGFR2,SU 4949,SU-5214,Inhibitor,EGFR,SU-4949
- SU5214, 10 mM in DMSO
- 3-(2-METHOXYBENZYLIDENE)-3H-INDOL-2-OL
- SU5214 ，S6809
- CAS:
- 186611-04-1
- MF:
- C16H13NO2
- MW:
- 251.28
- Mol File:
- 186611-04-1.mol
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SU 5214 Chemical Properties
- Boiling point:
- 469.4±45.0 °C(Predicted)
- Density
- 1.238±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMF: 33 mg/ml; DMSO: 33 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml
- form
- A crystalline solid
- pka
- 12.81±0.20(Predicted)
- color
- White to yellow
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SU 5214 Usage And Synthesis
Uses
SU5214 is a potent VEGFR2 inhibitor extracted from patent US5834504A, SU5214, has IC50s of 14.8 μM (FLK-1) and 36.7 μM (EGFR), respectively[1].
IC 50
Flk-1: 14.8 μM (IC50)
References
[1] Tang et al. 3-(2'-halobenzylidenyl)-2-indolinone compounds for the treatment of disease. US5834504A.
SU 5214Supplier
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
- Tel
- 025-66113011 17798518460
- cfzhang@aikonchem.com
Shanghai JiYi Biotechnology Co. Ltd.
- Tel
- 13621943973
- sales@shjiyipharmatech.com
Shanghai YuanYe Biotechnology Co., Ltd.
- Tel
- 021-61312847; 18021002903
- 3008007409@qq.com
Tianjin Kailiqi Biotechnology Co., Ltd.
- Tel
- 15076683720
- klq@cw-bio.com
ShangHai Biochempartner Co.,Ltd
- Tel
- 177-54423994 17754423994
- 2853530910@QQ.com
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SU 5214(186611-04-1)Related Product Information
- WAY-607500
- SU14813
- CIVENTICHEM CV-409
- SU5402
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- SU5208
- 5-CHLORO-3-[(3,5-DIMETHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE
- VEGFR2 Kinase Inhibitor I
- IC 261
- NSC 247030
- 3-(4-ISOPROPYLBENZYLIDENYL)INDOLIN-2-ONE
- SUN11602
- SU 4942
- SU 11274
- SU 5205
- (E)-2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropyl)acrylamide
- SU 4312