MK-0941 Chemical Properties

storage temp. 

Store at -20°C

solubility 

DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 5 mg/ml

form 

A crystalline solid

color 

Light yellow to yellow

MK-0941 Usage And Synthesis

Uses

MK-0941 is a potent, orally active and allosteric glucokinase activator, with EC50s of 240 and 65 nM for recombinant human glucokinase in the presence of 2.5 and 10 mM glucose, respectively. MK-0941 has potential in the treatment of type 2 diabetes[1].

References

[1] Eiki J, et al. Pharmacokinetic and pharmacodynamic properties of the glucokinase activator MK-0941 in rodent models of type 2 diabetes and healthy dogs. Mol Pharmacol. 2011 Dec;80(6):1156-65. DOI:10.1124/mol.111.074401

MK-0941(1137916-97-2)Related Product Information

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