ChemicalBook > Product Catalog > API > Antineoplastic agents > Antibiotics anticancer drugs > Pirarubicin
Pirarubicin
Pirarubicin Basic information
- Product Name:
- Pirarubicin
- Synonyms:
-
- THP-ADM
- THEPRUBICIN
- (8s-cis)-droxyacetyl)-1-methoxy
- (8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
- Tepirubicin
- Therarubiein
- THP-adriamycin
- (8S,10S)-10-[(2S,4S,5S,6S)-4-Amino-6-methyl-5-[(2S)-oxan-2-yl]oxy-oxan-2-yl]oxy-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione
- CAS:
- 72496-41-4
- MF:
- C32H37NO12
- MW:
- 627.64
- Product Categories:
-
- Inhibitors
- API
- Chiral Reagents
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Mol File:
- 72496-41-4.mol
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Pirarubicin Chemical Properties
- Melting point:
- 188-192°C (dec.)
- alpha
- D25 +175 ±25° (c = 0.2 in CHCl3)
- Boiling point:
- 834.7±65.0 °C(Predicted)
- Density
- 1.51±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- ethanol: soluble25mg/mL
- form
- powder
- pka
- 7.35±0.60(Predicted)
- color
- Orange to Red
- Stability:
- Hygroscopic
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MSDS
- Language:English Provider:Pirarubicin
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Pirarubicin Usage And Synthesis
Description
Pirarubicin is a new anthracycline anticancer agent structurally related to doxorubicin. In acute leukemia, non-Hodgkin’s lymphoma, breast and ovariail carcinoma, pirarubicin is reportedly superior to doxorubicin and better tolerated. Its major side-effect appears to be myelosuppression, mainly in the form of leucopenia, which is potentially dose-limiting.
Chemical Properties
Red Solid
Originator
Meiji Seika (Japan)
Uses
Structural analog of Doxorubicin. Antineoplastic.
Definition
ChEBI: (7S,9S)-7-[[(2R,4S,5S,6S)-4-amino-6-methyl-5-[[(2R)-2-oxanyl]oxy]-2-oxanyl]oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione is an anthracycline.
brand name
Pinorubicin; Therarubucin
Pirarubicin Preparation Products And Raw materials
Raw materials
PirarubicinSupplier
Shanghai Mokai Pharmaceutical Technology Co., Ltd. Gold
- Tel
- 021-60951261 18601606476
- nancy@mkpharma.cn
Jiangxi ravel Biotechnology Co.,Ltd Gold
- Tel
- 18502762009
- 721846333@qq.com
Shanghai Boyle Chemical Co., Ltd.
- Tel
- sales@boylechem.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Chembest Research Laboratories Limited
- Tel
- 021-20908456
- sales@BioChemBest.com
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Pirarubicin(72496-41-4)Related Product Information
- Doxorubicinone
- Chrysophanic acid
- Idarubicin hydrochloride
- Adriamycin
- 2-(HYDROXYMETHYL)ANTHRAQUINONE
- Pirarubicin
- 1,8-Dihydroxyanthraquinone
- 1,2,3,4-TETRAHYDRO-1,5-NAPHTHALENEDIOL
- 3,4-DIMETHYL-3'-METHOXYBENZOPHENONE
- 2-METHOXY-4'-METHYLBENZOPHENONE
- 2-METHOXY-3'-METHYLBENZOPHENONE
- 14-Hydroxy Carminomycin
- 2,4-DIMETHYL-3'-METHOXYBENZOPHENONE
- Carubicin
- 4-ETHYL-2'-METHOXYBENZOPHENONE
- L-DaunosamineHCl
- 3-METHOXY-3'-METHYLBENZOPHENONE
- ISLANDICIN