TAMRA-Azide-PEG-Biotin Chemical Properties

solubility 

Soluble in Water, DMSO, DMF, DCM

form 

Solid

color 

Purple to purplish red

TAMRA-Azide-PEG-Biotin Usage And Synthesis

Description

TAMRA-Azide-PEG-Biotin is a TAMRA dye biotin reagent containing a biotin group and an azide group, which enables Click Chemistry-mediated labeling of alkyne-tagged proteins. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

TAMRA-Azide-PEG-biotin is a dye derivative of TAMRA (HY-135640). TAMRA-Azide-PEG-biotin contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

TAMRA-Azide-PEG-Biotin(1797415-74-7)Related Product Information

• TAMRA-PEG3-Azide
• TAMRA-PEG4-alkyne
• TAMRA-PEG4-DBCO
• TAMRA-Azide-PEG-Desthiobiotin