2-Methoxypyridin-3-amine Chemical Properties

Melting point:

67 °C

Boiling point:

118°C/13mmHg(lit.)

Density 

1.139±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

soluble in Methanol

form 

powder to crystal

pka

4.33±0.10(Predicted)

color 

Orange to Brown to Dark red

InChI

InChI=1S/C6H8N2O/c1-9-6-5(7)3-2-4-8-6/h2-4H,7H2,1H3

InChIKey

YXFAOWYMDGUFIQ-UHFFFAOYSA-N

SMILES

C1(OC)=NC=CC=C1N

CAS DataBase Reference

20265-38-7(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

20/21/22-36/37/38-41-37/38-22

Safety Statements 

26-36/37/39-39

HazardClass 

IRRITANT

HS Code 

29339900

2-Methoxypyridin-3-amine Usage And Synthesis

Uses

2-Methoxy-3-aminopyridine can be used as an intermediate in pharmaceutical chemistry and organic synthesis. In synthetic transformations, the amino group on the pyridine ring can be diazotized and then further derivatized, for example, by in-situ reduction to hydrazine compounds. Furthermore, under appropriate halogenation conditions, a halogen atom can be introduced at the fourth position of pyridine.

Chemical Properties

Reddish brown solid

Definition

ChEBI: 2-Methoxypyridin-3-amine is an aminopyridine.

References

[1] Tetrahedron, 1997, vol. 53, # 37, p. 12505 - 12524
[2] Patent: US2011/237791, 2011, A1. Location in patent: Page/Page column 63
[3] Patent: US5652363, 1997, A
[4] Patent: WO2005/26137, 2005, A2. Location in patent: Page/Page column 233
[5] Bulletin de la Societe Chimique de France, 1992, # 1, p. 79 - 84

2-Methoxypyridin-3-amine(20265-38-7)Related Product Information

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