6-Bromopurine Chemical Properties

Melting point:

>300 °C (lit.)

Boiling point:

240.9±50.0 °C(Predicted)

Density 

2.28±0.1 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

7.39±0.20(Predicted)

color 

Pale Beige

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

RTECS 

UO7513000

HS Code 

29339900

MSDS

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6-Bromopurine Usage And Synthesis

Description

6-Bromopurine is a 6-halogenated purine nucleoside analogue. Studies have shown that 6-halogenopurine inhibits tumour growth when combined with azaserine, which may be related to the blockage of guanine nucleotide biosynthesis. The inhibitory effect of bromopurine occurs between inosine 5‘-phosphate and guanosine 5’-phosphate. 6-Bromopurine also enhances the carcinostatic activity of azaserine. In addition, 6-Bromopurine is also used as an intermediate in the synthesis of Idelalisib.

Chemical Properties

Dark yellow crystalline powder

Uses

6-Bromopurine was used in the synthesis of 6-halopurine alkynes and corresponding triazole derivatives. 6-Bromopurine was used in the synthesis and chemical characterization of 2,3,4,5-tetrahydro-1,5-benzoxazepines-3-ol.

General Description

6-Bromopurine enhances the carcinostatic activity of azaserine in a test system employing ascites cell forms of sarcoma 180 and Ehrlich carcinoma in vivo. 6-bromopurine nucleosides are excellent substrates for substitution reactions with N-, O-, and S-containing nucleophiles in polar solvents.

6-Bromopurine(767-69-1)Related Product Information

• 6-Hydroxypurine
• Propanamide, N-(6,7-dihydro-6-oxo-1H-purin-2-yl)-2-methyl-
• Guanine
• Purine
• Adenine
• Azathioprine
• 3-Bromoanisole
• Allopurinol
• Bromine
• 2,6-Dibromopurine
• 2-AMINO-6-BROMOPURINE,d2-Amino-6-bromopurine
• 6-Amino-2-bromopurine
• 6-Amino-8-bromopurine riboside, 8-Bromoadenine-9-β-D-ribofuranoside,6-AMINO-8-BROMOPURINE RIBOSIDE
• 2,6-DIBROMOPURINE
• 2-bromopurine
• 6-Bromopurine
• 8-Bromopurine
• 6-Bromo-2’deoxynebularine