Cyanine3 amine Chemical Properties

solubility 

Soluble in Water, DMSO, DMF, DCM

Appearance

Red solid

ex/em

554/566 nm (PBS buffer)

ε(extinction coefficient)

150000 L⋅mol−1⋅cm−1

Φ(quantum yield)

0.31

Cyanine3 amine Usage And Synthesis

Description

Cy3 amine is a functionalized cyanine dye containing a free amine group, which can be conjugated with reactive groups such as NHS esters, carboxy groups, epoxides, etc.

Chemical Properties

Appearance: Red solid
ex/em: 554/566 nm (PBS buffer)
Extinction coefficient (ε): 150000 L??mol??1??cm??1
Quantum yield (Φ): 0.31

Uses

Cyanine3 amine hydrochloride, an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine hydrochloride has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λex=555 nm, λem=570 nm)[1].

References

[1] Zhang C, et, al. Influence of size, crosslinking degree and surface structure of poly(N-vinylcaprolactam)-based microgels on their penetration into multicellular tumor spheroids. Biomater Sci. 2019 Nov 1;7(11):4738-4747. DOI:10.1039/c9bm01132c

Abs/Em Maxima

555/570 nm

Fluoresene quantum yield

0.31

Extinction Coefficient

150000

CF260

0.04

CF280

0.09

Cyanine3 amine(2247688-56-6)Related Product Information

• Cyanine3 NHS ester