Sodium diethyldithiocarbamate trihydrate Chemical Properties

Melting point:

95-98.5 °C(lit.)

Density 

1.100

vapor density 

5.9 (vs air)

storage temp. 

room temp

solubility 

H₂O: passes test

form 

Crystals or Powder

color 

White to off-white

PH

7 (20g/l, H2O, 20℃)

Odor

Odorless

PH Range

11.6

Water Solubility 

FREELY SOLUBLE

Sensitive 

Hygroscopic

Merck 

14,3378

BRN 

3920507

Stability:

Stable. Incompatible with strong oxidizing agents. Hygroscopic.

CAS DataBase Reference

20624-25-3(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

22-38-41-36/37/38

Safety Statements 

26-39-37/39-36

RIDADR 

UN 3077 9 / PGIII

WGK Germany 

3

RTECS 

EZ6550000

TSCA 

Yes

HS Code 

29302000

Toxicity

LD50 orally in Rabbit: 1500 mg/kg LD50 dermal Rat > 1000 mg/kg

MSDS

• Language:English Provider:Diethyldithiocarbamic acid sodium salt trihydrate
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Sodium diethyldithiocarbamate trihydrate Usage And Synthesis

Chemical Properties

white to light yellow crystals

Uses

Sodium diethyldithiocarbamate trihydrate is a spin trapping reagent used in conjunction with ferrous ion to detect nitric oxide in brain, kidney, liver and other tissues. It is used as sensitive reagent for the determination of copper, rubber vulcanization accelerator and finds application in the determination of other metals such as zinc, cobalt, platinum and palladium. Furthermore, it is an inhibitor of superoxide dismutase, ascorbate oxidase and other enzymes as well as inhibits the induction of macrophage nitric oxide synthase.

Uses

Spin trap used in conjunction with Fe2+ to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO2 has been reported. Sodium diethyldithiocarbamate trihydrate is a copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.

Uses

A possible nuclear factor kappa B inhibitor.

General Description

Sodium diethyldithiocarbamate trihydrate may be used:

• To synthesize cis-dichlorobis(N,N-diethyldithiocarbamato) tin(IV) by reacting with tin(II) chloride.
• As an alternative to xanthates to generate carbamoyl radical precursors.
• To synthesize a soluble precursor polymer for poly(thienylene vinylene).
• To synthesize dichlorotetrakis(dimethyl sulfoxide)ruthenium (II), which can be a precursor to prepare other ruthenium complexes.[17}

Biochem/physiol Actions

Inhibits induction of macrophage nitric oxide synthase.

Purification Methods

Recrystallise it from water. [Beilstein 4 III 224, 4 IV 390.]

Sodium diethyldithiocarbamate trihydrate(20624-25-3)Related Product Information

• Diethyl disulfide
• Sodium citrate
• SILVER DIETHYLDITHIOCARBAMATE
• Sodium thiosulfate pentahydrate
• Dithiooxamide
• Sodium chlorite
• Sodium chloride
• Sodium hydroxide
• Sodium bicarbonate
• Sodium formate
• Diclofenac sodium
• Sodium acetate
• Sodium benzoate
• Trisodium phosphate
• S-SODIUM ETHANETHIOSULFONATE
• 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT
• Sodium dichloroacetate
• Sodium dichloroisocyanurate