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Eltrombopag Impurity 1

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Eltrombopag Impurity 1 Basic information

Product Name:
Eltrombopag Impurity 1
Synonyms:
  • (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxamide
  • DFBZGRQMLLZKDA-SLMZUGIISA-N
  • (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H- pyrazol-4-ylidene)hydrazineyl)-2'-hydroxy-[1,1'-biphenyl]-3- carboxamide
  • [1,1'-Biphenyl]-3-carboxamide, 3'-[(2Z)-2-[1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-
  • ltrombopag Impurity 5
  • ELTROMBOPAG AMIDE IMPURITY
  • Etrapopa Ethanolamine impurity 6
  • Eltrombopag Impurity R
CAS:
1246929-02-1
MF:
C25H23N5O3
MW:
441.48
Mol File:
1246929-02-1.mol
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Eltrombopag Impurity 1 Chemical Properties

Melting point:
>164°C (dec.)
Boiling point:
647.0±65.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
-1.25±0.40(Predicted)
form 
Solid
color 
Orange
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Eltrombopag Impurity 1 Usage And Synthesis

Uses

Eltrombopag Amide, s a metabolite of Eltrombopag (E508000), which is an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.

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