Timolol EP Impurity G Chemical Properties

Melting point:

>150°C (dec.)

Density 

1.93±0.1 g/cm3(Predicted)

storage temp. 

Hygroscopic, -20°C Freezer, Under inert atmosphere

solubility 

DMSO (Slightly), Methanol (Slightly, Heated)

form 

Solid

pka

-1.02±0.20(Predicted)

color 

White to Off-White

Stability:

Moisture Sensitive

Timolol EP Impurity G Usage And Synthesis

Uses

4-?(4-Morpholinyl)?-1,?2,?5-?thiadiazol-?3(2H)?-?one 1-Oxide (Timolol EP Impurity G; Timolol BP Impurity G) is an impurity of Timolol (T4437005), an antihypertensive, an adrenergic blocking agent (1); antiarrhythmic (class II); antianginal; antiglaucoma (2) and antihypertensive (3) agent.

Timolol EP Impurity G(75202-36-7)Related Product Information

• 4-MORPHOLIN-4-YL-1,2,5-THIADIAZOL-3-OL
• 1-Propanol,3-[(1,1-dimethylethyl)amino]-2-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]-oxy]-
• (S)-Timolol maleate
• (+)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
• Timolol
• 3-Chloro-4-morpholino-1,2,5-thiadiazole
• TiMolol IMpurity E
• Timolol EP Impurity H