Basic information Applications Description References Safety Supplier Related
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Icariin

Basic information Applications Description References Safety Supplier Related

Icariin Basic information

Product Name:
Icariin
Synonyms:
  • Horny goat weed extract
  • ICARIINE
  • ICARRIN
  • epimedium extract
  • Epimedium herb Ext
  • Epimedium P.E
  • Icariin, froM EpiMediuM davidii Franch
  • Icariin Min 90%
CAS:
489-32-7
MF:
C33H40O15
MW:
676.66
EINECS:
610-440-0
Product Categories:
  • Plant extracts
  • chemical reagent
  • pharmaceutical intermediate
  • Nutritional Ingredients
  • plant extract
  • Functional Products
  • Natural Plant Extract
  • The group of Epimedii
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Inhibitors
  • Standardized plant extract
  • API
  • Flavones
Mol File:
489-32-7.mol
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Icariin Chemical Properties

Melting point:
223-225 ºC
alpha 
D15 -87.09° (in pyridine)
Boiling point:
948.5±65.0 °C(Predicted)
Density 
1.55
RTECS 
DJ2980500
storage temp. 
room temp
solubility 
DMSO: soluble50mg/mL, clear, colorless to dark yellow
form 
Powder
pka
5.90±0.40(Predicted)
color 
light yellow to yellow
λmax
350nm(MeOH)(lit.)
Merck 
14,3617
InChIKey
TZJALUIVHRYQQB-XLRXWWTNSA-N
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29389090
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Icariin Usage And Synthesis

Applications

Icariin inhibits the ROS-dependent JNK and p38 pathways.

Description

Icariin is one of the major flavonoids of the herb Epimedium, which has long been used in Tranditional Chinese Medicine to treat bone fracture and prevent osteoporosis. Research has shown that icariin should be an effective component for the bone-strengthening activity of the herb Epimedium, and one of the possible mechanisms for this activity is to stimulate the proliferation and enhance the osteogenic differentiation of marrow stromal cells. Icariin is reported to prevent and treat sexual dysfunction related diseases and improve the use of vasoconstriction. Icariin is used to prepare angiotensin converting enzyme inhibitor medicines, which can be used to treat hypertension-complicated coronary diseases.

References

[1] K. M. Chen, B. F. Ge, H. P. Ma, X. Y. Liu, M. H. Bai, Y, Wang (2005) Icariin, a flavonoid from the herb Epimedium enhances the osteogenic differentiation of rat primary bone marrow stromal cells, 60, 939-942
[2] Patent CN 1199647C “Application of icariin in preparation of medicine for preventing and treating sexual dysfunction”
[3] Patent CN 104739851 A “New application of icariin, or icariin derivatives or icariin salt”

Chemical Properties

Light yellow to yellow solid

Uses

hepatoprotective

IcariinSupplier

Wuhan Yijia Biotechnology Co., Ltd Gold
Email
2013537414@qq.com
Products Intro
Product Name:Icraiin
CAS:489-32-7
Shaanxi Pioneer Biotech Co.,Ltd Gold
Tel
29-84385017-8010
Email
sales@pioneerbiotech.com
Products Intro
Product Name:Icariin
CAS:489-32-7
Purity:10%~98% Package:1KG;25KG Remarks:1KG;25KG
Shanghai Hewu Biotechnology Co., LTD Gold
Tel
021-57886085
Email
shhebio@126.com
Products Intro
Product Name:Icariin;
CAS:489-32-7
Purity:HPLC>98% Package:10mg 20mg 100mg 500mg 1g 10g Remarks:HPLC
J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833-
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Products Intro
Product Name:Icariin, 98%, from Epimedium brevicornu Maxim.
CAS:489-32-7
Purity:98% Package:100MG;25MG
INTATRADE GmbH
Tel
+49 3493/605464
Email
sales@intatrade.de
Products Intro
Product Name:Icariin min 90% Synonyms 3-[(6-Deoxy-alpha-L-mannopyranosyl)oxy]-7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
CAS:489-32-7
Remarks:NN00324