Icariin
Icariin Basic information
- Product Name:
- Icariin
- Synonyms:
-
- Horny goat weed extract
- ICARIINE
- ICARRIN
- epimedium extract
- Epimedium herb Ext
- Epimedium P.E
- Icariin, froM EpiMediuM davidii Franch
- Icariin Min 90%
- CAS:
- 489-32-7
- MF:
- C33H40O15
- MW:
- 676.66
- EINECS:
- 610-440-0
- Product Categories:
-
- Plant extracts
- chemical reagent
- pharmaceutical intermediate
- Nutritional Ingredients
- plant extract
- Functional Products
- Natural Plant Extract
- The group of Epimedii
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Inhibitors
- Standardized plant extract
- API
- Flavones
- Mol File:
- 489-32-7.mol
Icariin Chemical Properties
- Melting point:
- 223-225 ºC
- alpha
- D15 -87.09° (in pyridine)
- Boiling point:
- 948.5±65.0 °C(Predicted)
- Density
- 1.55
- RTECS
- DJ2980500
- storage temp.
- room temp
- solubility
- DMSO: soluble50mg/mL, clear, colorless to dark yellow
- form
- Powder
- pka
- 5.90±0.40(Predicted)
- color
- light yellow to yellow
- λmax
- 350nm(MeOH)(lit.)
- Merck
- 14,3617
- InChIKey
- TZJALUIVHRYQQB-XLRXWWTNSA-N
Safety Information
- Safety Statements
- 24/25
- WGK Germany
- 3
- HS Code
- 29389090
Icariin Usage And Synthesis
Applications
Icariin inhibits the ROS-dependent JNK and p38 pathways.
Description
Icariin is one of the major flavonoids of the herb Epimedium, which has long been used in Tranditional Chinese Medicine to treat bone fracture and prevent osteoporosis. Research has shown that icariin should be an effective component for the bone-strengthening activity of the herb Epimedium, and one of the possible mechanisms for this activity is to stimulate the proliferation and enhance the osteogenic differentiation of marrow stromal cells. Icariin is reported to prevent and treat sexual dysfunction related diseases and improve the use of vasoconstriction. Icariin is used to prepare angiotensin converting enzyme inhibitor medicines, which can be used to treat hypertension-complicated coronary diseases.
References
[1] K. M. Chen, B. F. Ge, H. P. Ma, X. Y. Liu, M. H. Bai, Y, Wang (2005) Icariin, a flavonoid from the herb Epimedium enhances the osteogenic differentiation of rat primary bone marrow stromal cells, 60, 939-942
[2] Patent CN 1199647C “Application of icariin in preparation of medicine for preventing and treating sexual dysfunction”
[3] Patent CN 104739851 A “New application of icariin, or icariin derivatives or icariin salt”
Chemical Properties
Light yellow to yellow solid
Uses
hepatoprotective
IcariinSupplier
- Tel
- 29-84385017-8010
- sales@pioneerbiotech.com
- Products Intro
- Product Name:Icariin
CAS:489-32-7
Purity:10%~98% Package:1KG;25KG Remarks:1KG;25KGG;KG
- Tel
- 021-57886085
- shhebio@126.com
- Products Intro
- Product Name:Icariin;
CAS:489-32-7
Purity:HPLC＞98% Package:10mg 20mg 100mg 500mg 1g 10g Remarks:HPLC
- Tel
- maryextract@126.com
- Products Intro
- Product Name:Epimedium Extract Icariin
CAS:489-32-7
Purity:10%,20%,98% Package:25Kg/Drum/
- Tel
- 010-82848833- ;010-82848833-
- jkinfo@jkchemical.com;market6@jkchemical.com
- Products Intro
- Product Name:Icariin, 98%, from Epimedium brevicornu Maxim.
CAS:489-32-7
Purity:98% Package:100MG;25MG
- Tel
- +49 3493/605464
- sales@intatrade.de
- Products Intro
- Product Name:Icariin min 90% Synonyms 3-[(6-Deoxy-alpha-L-mannopyranosyl)oxy]-7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
CAS:489-32-7
Remarks:NN00324