8-AMINOGUANINE Chemical Properties

Melting point:

>330°C (dec.)

storage temp. 

-20°C Freezer, Under Inert Atmosphere

solubility 

Aqueous Base (Sparingly, Heated), DMSO (Very Slightly, Heated)

form 

powder

color 

white to beige

8-AMINOGUANINE Usage And Synthesis

Chemical Properties

Solid

Uses

8-Aminoguanine accelerates DNA tetramolecular G-quadruplex formation.

Biological Activity

8-Aminoguanine, a guanine derivative, is an orally available and highly efficacious potassium-sparing diuretic/natriuretic th at increased sodium excretion by 17.2-fold and decrease potassium excretion by 71.0%. 8-Aminoguanine increases glucose excretion by 12.1-fold. Also, 8-Aminoguanine suppressed deoxycorticosterone/salt-induced hypertension.

8-AMINOGUANINE(28128-41-8)Related Product Information

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• 2-amino-8-(4-morpholinyl)-1,9-dihydro-6H-purin-6-one