ChemicalBook > Product Catalog > Biochemical Engineering > Polypeptide > (ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676)
(ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676)
(ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676) Basic information
- Product Name:
- (ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676)
- Synonyms:
-
- (Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-676) trifluoroacetate salt
- A4 PROTEIN PRECURSOR770 (667-676)
- SER-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-ARG
- SEVNLDAEFR
- (ASN670,LEU671)-APP770 (667-676)
- (ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676)
- [ASN670, LEU671]AMYLOID-BETA
- BETA-SECRETASE SUBSTRATE II
- CAS:
- 186142-28-9
- MF:
- C50H78N14O19
- MW:
- 1179.24
- Product Categories:
-
- Amyloid Precursor ProteinsEnzyme Substrates
- beta-SecretaseEnzyme Substrates
- beta-SecretaseNeuropeptides
- Other Amyloid Protein Fragments
- Alzheimers and Neurodegenerative Disease Research
- Neurodegenerative Disease Peptides
- Protease Substrates
- Substrates by Enzyme
- β Amyloid Peptides
- Mol File:
- 186142-28-9.mol
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(ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676) Chemical Properties
- storage temp.
- -20°C
- form
- solid
- Sequence
- Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg
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(ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676) Usage And Synthesis
Uses
SEVNLDAEFR is a substrate for BACE1[1].
Biochem/physiol Actions
Substrate for assaying β-secretase activity that corresponds to the "Swedish" Lys-Met/Asn-Leu mutation of the amyloid precursor protein β-secretase cleavage site.
References
[1] Machálková M, et al. A label-free MALDI TOF MS-based method for studying the kinetics and inhibitor screening of the Alzheimer's disease drug target β-secretase. Anal Bioanal Chem. 2018 Nov;410(28):7441-7448. DOI:10.1007/s00216-018-1354-6
(ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676)Supplier
GL Biochem (Shanghai) Ltd
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- 21-61263452 13641803416
- ymbetter@glbiochem.com
Chemsky（shanghai）International Co.,Ltd.
- Tel
- 021-50135380
- shchemsky@sina.com
Sigma-Aldrich
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- 021-61415566 800-8193336
- orderCN@merckgroup.com
Creative Peptides
- Tel
- info@creative-peptides.com
Beijing Solarbio Science & Tecnology Co., Ltd.
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- 010-50973130 18101056239
- 3193328036@qq.com
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(ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676)(186142-28-9)Related Product Information
- AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676)
- MCA-(ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676)-LYS(DNP)-ARG-ARG AMIDE
- LYS(DABSYL)-(ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676)-GLN-LUCIFER YELLOW
- (ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676)
- SER-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-ARG TRIFLUOROACETATE SALT