ANTI-SPO11
ANTI-SPO11 Basic information
- Product Name:
- ANTI-SPO11
- Synonyms:
-
- ANTI-SPO11
- Anti-MGC39953
- Anti-SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
- Anti-SPO11 antibody produced in rabbit
- MW:
- 0
- Mol File:
- Mol File
ANTI-SPO11 Chemical Properties
- storage temp.
- -20°C
- form
- buffered aqueous solution
- biological source
- rabbit
ANTI-SPO11 Usage And Synthesis
Biological Activity
Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5μ end of DSBs and is essential for the formation of DSBs. SPO11 is similar in sequence and conserved features to the yeast meiotic recombination protein. It belongs to the TOP6A protein family. Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5μ end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described.