Basic information Safety Supplier Related

COCHLIOQUINONE B

Basic information Safety Supplier Related

COCHLIOQUINONE B Basic information

Product Name:
COCHLIOQUINONE B
Synonyms:
  • COCHLIOQUINONE B
  • 20-De(acetyloxy)-11-deoxy-20-oxocochlioquinone A
  • Pyrano[3,2-a]xanthene-8,11-dione, 9-[(1S,3S)-1,3-dimethyl-2-oxopentyl]-1,2,3,4a,5,6,6a,12,12a,12b-decahydro-3-(1-hydroxy-1-methylethyl)-6a,12b-dimethyl-, (3R,4aR,6aR,12aR,12bR)-
CAS:
32450-26-3
MF:
C28H40O6
MW:
472.61
Mol File:
32450-26-3.mol
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COCHLIOQUINONE B Chemical Properties

Boiling point:
579.4±50.0 °C(Predicted)
Density 
1.17±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form 
A solid
pka
14.54±0.29(Predicted)
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COCHLIOQUINONE B Usage And Synthesis

Uses

Cochlioquinone B, the minor component of a bioactive pigment isolated from Bipolaris leersia, is an NADH-ubiquinone reductase inhibitor and phytotoxic agent inhibiting root growth. It is closely related to Cochlioquinone A which inhibits diacylglycerol acyltransferase and exhibits anti-angiogenic and nematocidal activity. Cochlioquinones have recently been shown to be antagonists of the human chemokine receptor, CCR5, in HIV-1.

Uses

Cochlioquinone B is an NADH ubiquinonereductase inhibitor and a phytotoxic agent. A metabolite of Cochliobolus miyabeanus.

COCHLIOQUINONE BSupplier

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