COCHLIOQUINONE B
COCHLIOQUINONE B Basic information
- Product Name:
- COCHLIOQUINONE B
- Synonyms:
-
- COCHLIOQUINONE B
- 20-De(acetyloxy)-11-deoxy-20-oxocochlioquinone A
- Pyrano[3,2-a]xanthene-8,11-dione, 9-[(1S,3S)-1,3-dimethyl-2-oxopentyl]-1,2,3,4a,5,6,6a,12,12a,12b-decahydro-3-(1-hydroxy-1-methylethyl)-6a,12b-dimethyl-, (3R,4aR,6aR,12aR,12bR)-
- CAS:
- 32450-26-3
- MF:
- C28H40O6
- MW:
- 472.61
- Mol File:
- 32450-26-3.mol
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COCHLIOQUINONE B Chemical Properties
- Boiling point:
- 579.4±50.0 °C(Predicted)
- Density
- 1.17±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
- form
- A solid
- pka
- 14.54±0.29(Predicted)
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COCHLIOQUINONE B Usage And Synthesis
Uses
Cochlioquinone B, the minor component of a bioactive pigment isolated from Bipolaris leersia, is an NADH-ubiquinone reductase inhibitor and phytotoxic agent inhibiting root growth. It is closely related to Cochlioquinone A which inhibits diacylglycerol acyltransferase and exhibits anti-angiogenic and nematocidal activity. Cochlioquinones have recently been shown to be antagonists of the human chemokine receptor, CCR5, in HIV-1.
Uses
Cochlioquinone B is an NADH ubiquinonereductase inhibitor and a phytotoxic agent. A metabolite of Cochliobolus miyabeanus.
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