S-ETHYL TRIFLUOROTHIOACETATE Chemical Properties

Boiling point:

90.5 °C(lit.)

Density 

1.234 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.376(lit.)

Flash point:

39 °F

storage temp. 

Store at RT.

form 

clear liquid

color 

Colorless to Light yellow

BRN 

1761564

CAS DataBase Reference

383-64-2(CAS DataBase Reference)

EPA Substance Registry System

Ethanethioic acid, trifluoro-, S-ethyl ester (383-64-2)

Safety Information

Hazard Codes 

F,Xi

Risk Statements 

11-36/37/38

Safety Statements 

16-26-36

RIDADR 

UN 3272 3/PG 2

WGK Germany 

3

F 

3-9-13-21

Hazard Note 

Flammable/Irritant

HazardClass 

3.1

PackingGroup 

II

HS Code 

2918300090

MSDS

• Language:English Provider:SigmaAldrich

S-ETHYL TRIFLUOROTHIOACETATE Usage And Synthesis

Chemical Properties

clear colorless to slightly yellow liquid

Uses

S-Ethyl trifluorothioacetate was used to selectively trifluoroacetylate amino groups in proteins.

Synthesis Reference(s)

Journal of the American Chemical Society, 74, p. 4005, 1952 DOI: 10.1021/ja01136a010

Purification Methods

If IR is free of OH bands then fractionally distil it; otherwise dilute the thio-ester with dry Et2O, wash with 5% KOH and H2O, dry over MgSO4 and fractionate it through an efficient column [Hauptschein et al. J Am Chem Soc 74 4005 1952]. [Beilstein 2 IV 567.] Powerful obnoxious odour.

S-ETHYL TRIFLUOROTHIOACETATE(383-64-2)Related Product Information

• S-ETHYL TRIFLUOROTHIOACETATE
• 2,2,2-TRIFLUOROETHANETHIOL
• Fluoroacetic acid
• ethyl ethanethioate
• 1,1'-Thiobisethane
• Sulphur
• METHYL MERCAPTAN
• Fluoroacetaldehyde
• S-METHYL THIOACETATE
• Ethanethiol
• Hydrogen Sulfide
• Thioacetic acid
• Dimethyl sulfide
• Methylthioethane
• Difluoroethane
• TRIFLUOROACETALDEHYDE
• S-ETHYL-TRIFLUOROTHIOACETATE = TRIFLUOROTHIOACETIC ACID S-ETHYL ESTER