N-(tert-Butyl)decahydroisoquinoline-3-carboxamide CAS#: 136465-81-1

N-(tert-Butyl)decahydroisoquinoline-3-carboxamide Basic information

Product Name:

N-(tert-Butyl)decahydroisoquinoline-3-carboxamide

Synonyms:

TIMTEC-BB SBB009946
N-(TERT-BUTYL)DECAHYDROISOQUINOLINE-3-CARBOXAMIDE
(S)-T-BUTYL-DECAHYDRO-3-ISOQUINOLINE CARBOXAMIDE
(S)-(-)-TERT-BUTYL-DECAHYDRO-3-ISOQUINOLINECARBOXAMIDE
(S)-TERT-BUTYL DECAHYDRO-3-ISOQUINOLINECARBOXAMIDE
(3S,4aS,8aS)-N-(1,1-DiMethylethyl)decahydro-3-isoquinolinecarboxaMide
(3S,4aS,8aS)-Decahydroisoquinoline-3-carboxylic acid tert-butylaMide
3-IsoquinolinecarboxaMide, N-(1,1-diMethylethyl)decahydro-, [3S-(3α,4aβ,8aβ)]-

CAS:

136465-81-1

MF:

C14H26N2O

MW:

238.37

EINECS:

420-380-5

Product Categories:

Nelfinavir
Aromatics
Building Blocks for HIV Protease InhibitorsChiral Building Blocks
Cell Signaling Enzymes
Heterocyclic Building Blocks
Chiral Reagents
HIV Protease Reagents&Envelope Proteins
Isoquinolines
136465-81-1

Mol File:

136465-81-1.mol

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N-(tert-Butyl)decahydroisoquinoline-3-carboxamide Chemical Properties

Melting point:: 112-115 °C(lit.)
alpha: -70 º
Boiling point:: 380.97°C (rough estimate)
Density: 1.09
vapor pressure: 0.001-0.01Pa at 25-40℃
refractive index: 1.4590 (estimate)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka: 15.65±0.20(Predicted)
form: powder to crystal
color: White to Almost white
optical activity: [α]22/D 71°, c = 1 in methanol
Surface tension: 51.9mN/m at 1g/L and 20℃
Dissociation constant: 8.64 at 24℃
CAS DataBase Reference: 136465-81-1(CAS DataBase Reference)

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Safety Information

Hazard Codes: Xi,Xn
Risk Statements: 22-41-52/53
Safety Statements: 24/25-61-39-26-22
WGK Germany: 3
Hazard Note: Irritant
HS Code: 29334900

MSDS

Language:English Provider:ACROS
Language:English Provider:SigmaAldrich

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N-(tert-Butyl)decahydroisoquinoline-3-carboxamide Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

Fragment present in various HIV-1 protease inhibitors currently in clinical trials for AIDS treatment.

Uses

Intermediate in the production of HIV protease inhibitors

N-(tert-Butyl)decahydroisoquinoline-3-carboxamideSupplier

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