(ACETYLMETHYLENE)TRIPHENYLPHOSPHORANE Chemical Properties

Melting point:

203-205 °C (lit.)

Boiling point:

478.5±28.0 °C(Predicted)

Density 

1.14

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Soluble in chloroform. Slightly soluble in methanol.

form 

Powder

color 

White to off-white

Sensitive 

Air Sensitive

BRN 

750077

Stability:

Stable. Combustible. Incompatible with strong oxidizing agents.

CAS DataBase Reference

1439-36-7(CAS DataBase Reference)

Safety Information

Risk Statements 

22-36/37/38

Safety Statements 

22-24/25

WGK Germany 

3

RTECS 

UC3900000

HS Code 

29319090

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

(ACETYLMETHYLENE)TRIPHENYLPHOSPHORANE Usage And Synthesis

Chemical Properties

white to light beige crystalline powder

Uses

(Acetylmethylene)triphenylphosphorane is used as a Wittig reagent in synthetic chemistry, especially for the synthesis of functionalized pyrrolidines and cyclobutanones. It plays as a vital role in asymmetric allylboration for enantioselective synthesis of (+)-awajanomycin.It is also employed as a reactant in the preparation of 1,2-dioxanes with antitrypanosomal activity. Further, it is used in the preparation of amphibian pyrrolizidine alkaloids through allylic aminations and silicon-containing acyclic dienone musk odorants. In addition to this, it is involved in Domino Suzuki/Heck coupling reactions to prepare fluorenylidenes.

(ACETYLMETHYLENE)TRIPHENYLPHOSPHORANE(1439-36-7)Related Product Information

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• PalBociclib Impurity 17
• PalBociclib Impurity 24
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• PalBociclib Impurity 14
• 8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-6-vinylpyrido[2,3-d]pyrimidin-7(8H)-one
• tert-Butyl 4-(6-((6-(1-butoxyvinyl)-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate
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• Palbociclib Impurity 20
• Palbociclib Impurity 10
• Palbociclib Impurity 2
• PalBociclib Impurity 11