6-Chloropurine ribonucleoside Chemical Properties

Melting point:

158-162 °C (dec.)(lit.)

Boiling point:

614.8±65.0 °C(Predicted)

Density 

1.7303 (rough estimate)

refractive index 

-45 ° (C=0.8, H2O)

storage temp. 

Sealed in dry,Store in freezer, under -20°C

form 

Powder

pka

13.06±0.70(Predicted)

color 

Yellow to Green

CAS DataBase Reference

2004-06-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

22-24/25-36-26

RTECS 

UO7520800

F 

10-23

Hazard Note 

Irritant

HS Code 

29389090

MSDS

• Language:English Provider:6-Chloropurine riboside
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

6-Chloropurine ribonucleoside Usage And Synthesis

Chemical Properties

white to light yellow crystal powde

Uses

6-CHLOROPURINE RIBOSIDE acts as a reactant in the synthesis of isozyme-specific enzyme inhibitors as well as in the preparation of dog coronary artery receptor agonists.

Purification Methods

Purify the riboside by suspending the dry solid (~12 g) in hot MeOH (130 mL) and then adding enough hot H2O (~560mL) to cause solution, filter and set aside at 5o overnight. The colourless crystals of the riboside are filtered off, washed with Me2CO, Et2O and dried at 60o/0.1mm. More material can be obtained by evaporating the filtrate to dryness and recrystallisation of the residue from MeOH/H2O (2:1) (15mL/g). It has max 264nm ( 9140) in H2O. [Robins Biochemical Preparations 10 145 1963, Baker et al. J Org Chem 22 954 1957.]

6-Chloropurine ribonucleoside(2004-06-0)Related Product Information

• 6-Chloropurine
• Inosine
• NUCLEOSIDE PHOSPHORYLASE BACTERIAL
• 2-Amino-6-chloropurine-9-riboside
• 2,6-Dichloropurine riboside
• 6-Chloro-9-beta-D-(2,3-isopropylidene)ribofuranosylpurine
• 6-Chloropurine riboside,6-CHLOROPURINE RIBOSIDE, 99+%, PURE,6-Chloropurine riboside, pure
• 6-AMINO-2-CHLOROPURINE RIBOSIDE HEMIHYDRATE
• 2-Chloroadenosine
• Purine
• ACETIC ACID (2R,3R,4R,5R)-3,4-DIACETOXY-5-(6-CHLORO-2-IODO-PURIN-9-YL)-TETRAHYDRO-FURAN-2-YLMETHYL ESTER
• 2,3,5-Tri-O-acetyl-6-chloropurine-9-b-D-ribofuranoside
• 6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine
• 6-Chloropurine riboside 3'',5''-cyclic monophosphoric acid sodium salt,6-CHLOROPURINE RIBOSIDE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
• 2-ACETAMIDO-6-CHLORO-9-(2',3',5'-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL)PURINE
• 2',3',5'-Tri-O-acetyl-2-aMino-6-chloropurine Riboside
• 9-[2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL]-2,6-DICHLOROPURINE
• 6-CHLOROPURINE RIBOSIDE-5'-DIPHOSPHATE SODIUM SALT