Tiludronic acid Chemical Properties

Melting point:

174-177 °C

Boiling point:

600.7±65.0 °C(Predicted)

Density 

1.82±0.1 g/cm3(Predicted)

storage temp. 

room temp

solubility 

H2O: >10mg/mL, clear

pka

pK1 10.85; pK2 6.90; pK3 2.95; pK4 1.30(at 25℃)

form 

powder

color 

white to off-white

Safety Information

WGK Germany 

3

Tiludronic acid Usage And Synthesis

Definition

ChEBI: Tiludronic acid is an organochlorine compound.

Veterinary Drugs and Treatments

Tiludronate disodium (tiludronic acid) is a bisphosphonate bone resorption inhibitor that is available in some countries for the intravenous treatment of navicular disease in horses. Treatment earlier in the course of the disease apparently results in greater efficacy.
For humans, there is an orally administered FDA-approved product for treating Paget’s disease (osteitis deformans).

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