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BARBITAL

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BARBITAL Basic information

Product Name:
BARBITAL
Synonyms:
  • barbital free acid crystalline--dea*schedule iv I
  • barbital methanol solution
  • Barbital(barbitone)
  • BARBITAL FREE ACID CRYSTALLINE--DEASCHED ULE IV ITE
  • BARBITAL, FOR ANALYTICAL PURPOSE (EXPORT CONTROL)
  • BarbitonePh.Eur.+++
  • BARBITAL 99% GR
  • BARBITAL,POWDER,PURIFIED
CAS:
57-44-3
MF:
C8H12N2O3
MW:
184.19
EINECS:
200-331-2
Product Categories:
  • Pyrimidines
  • RECI
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
57-44-3.mol
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BARBITAL Chemical Properties

Melting point:
188-192°C
Boiling point:
318.14°C (rough estimate)
Density 
1.2200
refractive index 
1.4200 (estimate)
Flash point:
11 °C
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
7.43(at 25℃)
color 
Faintly bitter crystals from H2O; polymorphicforms; triagonal crystals, monoclinic prisms, monoclinicneedles, and triclinic cryst
Water Solubility 
7.149g/L(25 ºC)
Merck 
13,965
EPA Substance Registry System
5,5-Diethylbarbituric acid (57-44-3)
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Safety Information

Hazard Codes 
Xn,T,F
Risk Statements 
22-39/23/24/25-23/24/25-11-63-40-20
Safety Statements 
36-45-36/37-16-7
RIDADR 
UN 1230 3/PG 2
WGK Germany 
3
RTECS 
CQ3500000
Toxicity
LDLo orl-cat: 280 mg/kg PHREA7 19,472,39
DEA Controlled Substances
CSCN: 2145
CSA SCH: Schedule IV
NARC: No

MSDS

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BARBITAL Usage And Synthesis

Description

Barbital is an analytical reference material that is categorized as a barbiturate. It acts as an agonist at GABAA receptors to induce central nervous system depression. Formulations containing barbital have been used as a sedative to treat insomnia and seizures in human and veterinary medicine. Barbital is regulated as a Schedule IV compound in the United States. This product is intended for research and forensic applications.

Description

Barbital (CRM) (Item No. 22854) is a certified reference material categorized as a barbiturate. Barbital is regulated as a Schedule IV compound in the United States. Barbital (CRM) (Item No. 22854) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.

Chemical Properties

White crystals or powder; bitter taste; odorless. Stable in air. Soluble in hot water, alcohol, ether, acetone, and ethyl acetate.

Uses

Prototype of the barbiturate hypnotics.

Definition

ChEBI: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by two ethyl groups. Formerly used as a hypnotic (sleeping aid).

brand name

Dormileno;Escoderm;Hypnogene;Hypnox;Lidor;Megal;Plexonal;Somnytic tablets;Verinogen;Verodon;Veroletten;Verolitten;Veronigen.

World Health Organization (WHO)

Barbital is a long-acting barbiturate which is controlled under Schedule IV of the 1971 Convention on Psychotropic Substances. See WHO comment for barbiturates. (Reference: (UNCPS4) United Nations Convention on Psychotropic Substances (IV), , , 1971)

Safety Profile

Poison by ingestion, intravenous,intraperitoneal, and subcutaneous routes. Ingestion causespsychological effects in humans. Mutation data reported.When heated to decomposition it emits toxic fumes ofNOx. An hypnotic andsedative.

Purification Methods

Crystallise barbital from water or EtOH and dry it in a vacuum over P2O5. [Beilstein 24 III/IV 1901.]

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BARBITAL(57-44-3)Related Product Information