ACETYLSALICYLSALICYLIC ACID Chemical Properties

Melting point:

153-160 °C

Boiling point:

361.5°C (rough estimate)

Density 

1.346

refractive index 

1.4600 (estimate)

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Sparingly), DMSO (Sparingly), Methanol (Slightly)

pka

2.94±0.36(Predicted)

color 

White to Off-White

Water Solubility 

20mg/L(21 ºC)

EPA Substance Registry System

2-Carboxyphenyl 2-(acetyloxy)benzoate (530-75-6)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

24/25

HS Code 

29182900

MSDS

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ACETYLSALICYLSALICYLIC ACID Usage And Synthesis

Chemical Properties

white to almost white fine crystalline powder

Uses

Antiinflammatory;Cyclooxygenase inhibitor

Uses

analgesic, antipyretic

Uses

Acetylsalicylic Acid Impurity C

Definition

ChEBI: 2-[(2-acetyloxyphenyl)-oxomethoxy]benzoic acid is a carbonyl compound.

Purification Methods

Crystallise the analgesic from dilute AcOH or EtOH (m 161-162o), MeOH (m 165-168o), and *C6H6/EtOH (m 163-165o). Its solubilities in boiling Et2O, *C6H6 and EtOH are 1.4%, 2.2% and 33%, respectively. [Baker et al. J Chem Soc 201 1951, Garrett et al. J Am Pharm Soc 48 684 1959, Beilstein 10 I 41, 10 II 54, 10 IV 165.]

ACETYLSALICYLSALICYLIC ACID(530-75-6)Related Product Information

• 2-BENZOYLACETANILIDE
• Acetyl chloride
• 4-Hydroxybenzoic acid
• Sasapyrine
• Acetylsalicylic acid
• ACETYLSALICYLIC ANHYDRIDE
• ACETOXYVALERENIC ACID
• Acetic Aceclofenac
• 3-Hydroxybenzoic acid
• 4-amino-6-hydroxybenzene-1,3-dicarboxylic acid
• 2-Ethoxybenzoic acid
• ACETYLSALICYLIC ACID METHYL ESTER
• Methyl 2-ethoxybenzoate
• ACETYLSALICYLSALICYLIC ACID
• 2-BENZYLOXYBENZOIC ACID
• Phenyl salicylate
• 2-METHOXY-BENZOIC ACID PHENYL ESTER
• 2-BENZYLOXYBENZYL ALCOHOL