2-Bromopyrimidine Chemical Properties

Melting point:

55-57 °C (lit.)

Boiling point:

62-64°C (1.5 mmHg)

Density 

1.6448 (rough estimate)

refractive index 

1.5260 (estimate)

Flash point:

62-64°C/1.5mm

storage temp. 

-20°C

solubility 

DMSO (Sparingly), Methanol (Slightly)

form 

Crystalline Powder

pka

-1.59±0.13(Predicted)

color 

Off-white

Water Solubility 

Miscible with water.

BRN 

605945

CAS DataBase Reference

4595-60-2(CAS DataBase Reference)

NIST Chemistry Reference

Pyrimidine, 2-bromo-(4595-60-2)

EPA Substance Registry System

Pyrimidine, 2-bromo- (4595-60-2)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

TSCA 

Yes

HazardClass 

IRRITANT

HS Code 

29335990

MSDS

• Language:English Provider:2-Bromopyrimidine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2-Bromopyrimidine Usage And Synthesis

Chemical Properties

Off-white crystalline powder

Uses

2-Bromopyrimidine is used in the preparation of 2,7-bis(2-pyrimidyl)-9,9-dihexylfluorene by cross-coupling with 9,9-dihexylfluorene-2,7-diboronic acid. It undergoes microwave-assisted aminocarbonylation at C-2 with palladium and molybdenum hexacarbonyl.

Preparation

The recent synthesis of 2-bromopyrimidine by diazotization of 2-aminopyrimidine in hydrobromic acid has furnished a convenient starting material for other 2-substituted pyrimidines.

General Description

2-Bromopyrimidine undergoes microwave-assisited aminocarbonylation at C-2 with palladium and Mo(CO)_6.

2-Bromopyrimidine(4595-60-2)Related Product Information

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