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Methoxyacetic acid

Basic information Safety Supplier Related

Methoxyacetic acid Basic information

Product Name:
Methoxyacetic acid
Synonyms:
  • 2-methoxyaceticacid
  • CH3OCH2COOH
  • Glycollicacid,methylether
  • methoxy-aceticaci
  • Methoxyethanoic acid
  • Methylglycolicacid
  • RARECHEM AL BO 0106
  • Methoxyaceticacid,98%
CAS:
625-45-6
MF:
C3H6O3
MW:
90.08
EINECS:
210-894-6
Product Categories:
  • C1 to C5
  • Carbonyl Compounds
  • Carboxylic Acids
  • Building Blocks
  • C1 to C5
  • Carbonyl Compounds
  • Heterocyclic Compounds
  • Carboxylic Acids
  • Chemical Synthesis
  • Organic Building Blocks
Mol File:
625-45-6.mol
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Methoxyacetic acid Chemical Properties

Melting point:
7-9 °C (lit.)
Boiling point:
202-204 °C (lit.)
Density 
1.174 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.417(lit.)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform, Methanol (Slightly); Soluble in water, alcohol and oils.
form 
Liquid
pka
pK1:3.57 (25°C)
color 
Clear colorless to very slightly yellow
PH
1.6 (100g/l, H2O)
Odor
Peculiar fatty vinegear-like odor, in dilution fairly pleasant.
Water Solubility 
freely soluble
Sensitive 
Hygroscopic
BRN 
635800
LogP
-0.68
CAS DataBase Reference
625-45-6(CAS DataBase Reference)
NIST Chemistry Reference
Acetic acid, methoxy-(625-45-6)
EPA Substance Registry System
Methoxyacetic acid (625-45-6)
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Safety Information

Hazard Codes 
T
Risk Statements 
60-61-22-34
Safety Statements 
53-45
RIDADR 
UN 3265 8/PG 2
WGK Germany 
1
RTECS 
AI8650000
10-21
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
29189090

MSDS

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Methoxyacetic acid Usage And Synthesis

Chemical Properties

CLEAR COLOURLESS TO VERY SLIGHTLY YELLOW LIQUID

Uses

Methoxyacetic acid is used in zebrafish embryotoxicity test to evaluate chemical toxicity after exposure of the complete vertebrate embryo during embryogenesis. It is also used in industry as gelling, viscosity and stabilizer reagent.

Definition

ChEBI: A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is replaced by a methoxy group.

General Description

Colorless liquid.

Air & Water Reactions

Hygroscopic. Water soluble.

Reactivity Profile

Methoxyacetic acid is incompatible with alkalis and metals.

Health Hazard

ACUTE/CHRONIC HAZARDS: Methoxyacetic acid is corrosive.

Fire Hazard

Methoxyacetic acid is combustible.

Safety Profile

Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.

Synthesis

Methoxyacetic acid is prepared from Monochloroacetic acid with Sodium methylate.

Purification Methods

Fractionally crystallise the acid by repeated partial freezing, then fractionally distil it under vacuum through a vacuum-jacketed Vigreux column ~20cm long (p 11). [Beilstein 3 IV 574.]

Methoxyacetic acid Preparation Products And Raw materials

Preparation Products

Methoxyacetic acidSupplier

Shandong Zhengji Chemical Co. LTD Gold
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021-61259108 18621169109
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