5-CARBOXYCYTOSINE Chemical Properties

Melting point:

256-257 °C

Density 

1.88±0.1 g/cm3(Predicted)

storage temp. 

Refrigerator, under inert atmosphere

solubility 

Aqueous Base (Slightly)

form 

Solid

pka

-3.50±0.20(Predicted)

color 

Pale Yellow to Pale Beige

Safety Information

HazardClass 

IRRITANT

5-CARBOXYCYTOSINE Usage And Synthesis

Uses

Cytosine derivatives, such as 5-Carboxylcytosine, are involved with a wide variety of biological functions including cytosine methylation, gene expression, genome stability, and chromatin modification. In addition, 5-Carboxylcytosine interacts with the RNA polymerase II elongation complex that can influence the pluripotent states during early embryonic development.

Definition

ChEBI: A nucleobase analogue that is cytosine in which the hydrogen at position 5 is replaced by a carboxy group.

5-CARBOXYCYTOSINE(3650-93-9)Related Product Information

• 6-(HYDROXYMETHYL)URACIL
• 2,4-Dihydroxypyrimidine-5-carboxylic acid
• 2-(2-chloropyriMidin-5-yl)propan-2-ol
• 5,6-Diamino-1,3-dimethyluracil hydrate
• dihydro-6-imino-1,3-dimethyl-3H-pyrimidine-2,4,5-trione 5-oxime
• (E)-5-(2-BROMOVINYL)URACIL
• OROTIC ACID MONOHYDRATE
• dihydro-6-imino-1,3-dimethyluracil
• 6-FORMYL-URACIL MONOHYDRATE
• Pyrimidine, 4-(chloromethyl)-2,6-dimethoxy-
• Tetrahydrofuryluracil
• Pyrimidine, 5-chloro-4-(chloromethyl)-2,6-dimethoxy-
• Cytosine
• 5-Pyrimidinecarboxylic acid
• 5-CARBOXYCYTOSINE
• Pyrimidine-5-carboxaldehyde
• 2-Hydroxypyrimidine
• 5-HYDROXYMETHYLCYTOSINE