2',3'-O-Isopropylideneguanosine Chemical Properties

Melting point:

296 °C

Density 

1.93±0.1 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

solubility 

DMSO, 15% Ammonium Hydroxide, Hot 50% aq. Ethanol, Methanol, Warm Water

form 

Solid

pka

9?+-.0.20(Predicted)

color 

White to Off-White

InChI

InChI=1S/C13H17N5O5/c1-13(2)22-7-5(3-19)21-11(8(7)23-13)18-4-15-6-9(18)16-12(14)17-10(6)20/h4-5,7-8,11,19H,3H2,1-2H3,(H3,14,16,17,20)/t5-,7-,8-,11-/m1/s1

InChIKey

XKPDAYWPKILAMO-IOSLPCCCSA-N

SMILES

OC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)N)=O)N=C2)[C@@H]2OC(O[C@H]12)(C)C

CAS DataBase Reference

362-76-5(CAS DataBase Reference)

Safety Information

Safety Statements 

24/25

WGK Germany 

3

HS Code 

29349990

MSDS

• Language:English Provider:SigmaAldrich

2',3'-O-Isopropylideneguanosine Usage And Synthesis

Chemical Properties

White Crystalline Solid

Uses

A useful precursor for the preparation of nucleic acids.

Uses

2',3'-O-Isopropylideneguanosine is a useful precursor for the preparation of nucleic acids

Synthesis

Add 10 mL of anhydrous pyridine to 2 g (7.45 mmol) of solid 2',3'-O-Isopropylideneguanosine to form a white suspension.
1 Remove the pyridine under reduced pressure to remove any trapped water;
2 Repeat the previous step;
3 Add 5 mL of acetone to the residue and stir for 30 minutes;
4 Add 50 mL of ether to the mixture and stir for 1 hour;
5 Filter the resulting precipitate and wash it with ether;
6 Dry the product in a vacuum desiccator over P2O5.

2',3'-O-Isopropylideneguanosine(362-76-5)Related Product Information

• ISOPROPYLMAGNESIUM CHLORIDE
• Guanosine 5'-monophosphate disodium salt
• 5'-Guanylic acid
• Acyclovir
• (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol
• 2'-(O-METHYL)-INOSINE
• 1,3-Dioxolane-4-methanol
• 2'-O-Methylguanosine
• 2',3'-O-Isopropylideneinosine
• [(4S)-2,2-Dimethyl-1,3-dioxolan-4-yl]methanamine
• N,5'-O-Diacetyl-2',3'-O-isopropylideneguanosine
• 1,3,6-TRIOXACYCLOOCTANE
• (2,2-DIMETHYL-[1,3]-DIOXOLAN-4-YL)-METHYLAMINE
• 2',3'-O-Isopropylideneguanosine