(LEU31,PRO34)-NEUROPEPTIDE Y (PORCINE) Chemical Properties

storage temp. 

−20°C

solubility 

Soluble to 1 mg/ml in 0.25% acetic acid

form 

Powder

color 

White to off-white

Sequence

Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Leu-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Leu-Thr-Arg-Pro-Arg-Tyr-NH2

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

(LEU31,PRO34)-NEUROPEPTIDE Y (PORCINE) Usage And Synthesis

Uses

[Leu31,Pro34]- Neuropeptide Y (porcine), a Neuropeptide Y (NPY) analog, is a selective NPY Y1 receptor agonist. [Leu31,Pro34]- Neuropeptide Y (porcine) exhibits anxiolytic effects[1][2].

in vivo

IC 50

NPY Y₁ receptor

References

[1] Fuhlendorff J, et, al. [Leu31, Pro34]neuropeptide Y: a specific Y1 receptor agonist. Proc Natl Acad Sci U S A. 1990 Jan;87(1):182-6. DOI:10.1073/pnas.87.1.182
[2] Kokare DM, et, al. Interaction between neuropeptide Y and alpha-melanocyte stimulating hormone in amygdala regulates anxiety in rats. Brain Res. 2005 May 10;1043(1-2):107-14. DOI:10.1016/j.brainres.2005.02.038

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