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Cefetamet pivoxil hydrochloride

Basic information Uses Safety Supplier Related

Cefetamet pivoxil hydrochloride Basic information

Product Name:
Cefetamet pivoxil hydrochloride
Synonyms:
  • )(methoxyimino)acetyl)amino)-3-methyl-8-oxo-,(2,2-dimethyl-1-oxopropoxy)methy
  • 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-methyl-8-oxo-,(2,2-dimethyl-1-oxopropoxy)met5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicaci
  • monohydrochloride,(6r-(6-alpha,7-beta(z)))-leste
  • ro15-8075
  • CEFETAMET PIVOXIL HCL
  • CEFETAMET PIVOXIL HYDROCHLORIDE
  • (+)-(6r,7r)-pivaloyloxymethyl 7-[(2-amino-4-thiazolyl)
  • 7-[[2-(2-amino-4-thiazolyl)-2-methoxyimino-1-oxoethyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (2,2-dimethyl-1-oxopropoxy)methyl ester
CAS:
111696-23-2
MF:
C20H26ClN5O7S2
MW:
548.03
Mol File:
111696-23-2.mol
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Cefetamet pivoxil hydrochloride Chemical Properties

storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
DMSO : ≥ 100 mg/mL (182.47 mM);Water : < 0.1 mg/mL (insoluble)
form 
Solid
color 
White to off-white
InChIKey
XAAOHMIKXULDKJ-NAYWOEQTNA-N
SMILES
C(C1=C(CS[C@]2([H])[C@H](NC(=O)/C(/C3=CSC(N)=N3)=N\OC)C(=O)N12)C)(=O)OCOC(=O)C(C)(C)C.Cl |&1:5,7,r|
CAS DataBase Reference
111696-23-2(CAS DataBase Reference)
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Cefetamet pivoxil hydrochloride Usage And Synthesis

Uses

Cefotaxime hydrochloride is an oral third-generation broad-spectrum cephalosporin antibiotic with strong antibacterial activity against both Gram-positive and Gram-negative bacteria, and is stable against bacterial beta-lactamases. Clinically, it is suitable for lower respiratory tract infections, ear, nose, throat infections, and urinary tract infections caused by susceptible bacteria.

Description

Cefetamet pivoxil hydrochloride, an ester prodrug of cefetamet, is an orally active cephalosporin introduced for the treatment of community-acquired respiratory and urinary tract infections. Roche indicated that this drug will possibly be the first third-generation cephalosporin to be launched in some counrries. It is reportedly useful in penicillin-resistant pneumococci, gonococci and H. influenzae infections, but ineffective against Staphylococci, P. aeruginosa and some non-fermenters.

Originator

Takeda (Japan)

Definition

ChEBI: Cefetamet pivoxil hydrochloride is an organic molecular entity.

brand name

Globocef

Cefetamet pivoxil hydrochlorideSupplier

Zhejiang Yongning Pharmaceutical Co., Ltd. Gold
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Beijing HuaMeiHuLiBiological Chemical
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010-56205725
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Cefetamet pivoxil hydrochloride(111696-23-2)Related Product Information