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2,2'-DITHIOBIS(5-NITROPYRIDINE)

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2,2'-DITHIOBIS(5-NITROPYRIDINE) Basic information

Product Name:
2,2'-DITHIOBIS(5-NITROPYRIDINE)
Synonyms:
  • DTNP
  • BIS(5-NITRO-2-PYRIDYL) DISULFIDE
  • 2,2'-DITHIOBIS(5-NITROPYRIDINE)
  • 2,2’-dithiobis(5-nitro-pyridin
  • 1,2-Bis(5-nitropyridin-2-yl)disulfane
  • Bis(5-nitro-2-pyridyl) disulfide, DTNP
  • 5-nitro-2-(5-nitropyridin-2-yl)disulfanylpyridine
  • 5-nitro-2-(5-nitropyridin-2-yl)disulfanyl-pyridine
CAS:
2127-10-8
MF:
C10H6N4O4S2
MW:
310.31
EINECS:
218-344-7
Product Categories:
  • blocks
  • Pyridines
Mol File:
2127-10-8.mol
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2,2'-DITHIOBIS(5-NITROPYRIDINE) Chemical Properties

Melting point:
155-157 °C(lit.)
Boiling point:
139°C (rough estimate)
Density 
1.6508 (rough estimate)
refractive index 
1.6000 (estimate)
storage temp. 
Store at RT.
pka
-2.88±0.29(Predicted)
form 
solid
color 
Brown
BRN 
305413
CAS DataBase Reference
2127-10-8(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
36/37/39
WGK Germany 
3
RTECS 
UT2964000
HS Code 
2933399990

MSDS

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2,2'-DITHIOBIS(5-NITROPYRIDINE) Usage And Synthesis

Uses

2,2′-Dithiobis(5-nitropyridine) was employed:

  • as cysteine-activating reagent to study the NMR of G protein-coupled receptors
  • in the deprotection assays for protected selenocysteine-containing peptides
  • for deprotecting p-methoxybenzyl groups and acetamidomethyl groups from the side-chains of cysteine and selenocysteine
  • to remove the p-methoxybenzyl protecting group from cysteine and selenocysteine side-chains

General Description

2,2′-Dithiobis(5-nitropyridine) is an aromatic disulphide.

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