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1-Boc-4-(aminomethyl)piperidine

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1-Boc-4-(aminomethyl)piperidine Basic information

Product Name:
1-Boc-4-(aminomethyl)piperidine
Synonyms:
  • 1-Boc-4-(aminomethyl)piperidine, 1-Boc-4-piperidylmethylamine
  • 4-(aminometh
  • t-Butyl 4-(aminomethyl)piperidine-1-carboxylate
  • 1-Boc-4-(aminomethyl)piperidine ,97%
  • 4-(Aminomethyl)piperidine, N1-BOC protected 97%
  • 1-Boc-4-aminomethylpiperi...
  • 4-(Aminomethyl)-1-(tert-butoxycarbonyl)piperidine, tert-Butyl 4-(aminomethyl)piperidine-1-carboxylate
  • 1,1-DiMethylethyl 4-(aMinoMethyl)-1-piperidinecarboxylate
CAS:
144222-22-0
MF:
C11H22N2O2
MW:
214.3
Product Categories:
  • Heterocyclic Compounds
  • Building Blocks
  • pharmacetical
  • Piperidine
  • Heterocyclic Building Blocks
  • Piperidines
Mol File:
144222-22-0.mol
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1-Boc-4-(aminomethyl)piperidine Chemical Properties

Boiling point:
237-238 °C(lit.)
Density 
1.013 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.473(lit.)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in chloroform and methanol.
form 
Liquid or Low Melting Solid
pka
10.13±0.29(Predicted)
color 
Colorless to yellow
InChI
InChI=1S/C11H22N2O2/c1-11(2,3)15-10(14)13-6-4-9(8-12)5-7-13/h9H,4-8,12H2,1-3H3
InChIKey
KLKBCNDBOVRQIJ-UHFFFAOYSA-N
SMILES
N1(C(OC(C)(C)C)=O)CCC(CN)CC1
CAS DataBase Reference
144222-22-0(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi,C,N
Risk Statements 
36/37/38-34-50
Safety Statements 
26-36-45-36/37/39-24/25-23-61
RIDADR 
UN 3082 9 / PGIII
WGK Germany 
3
F 
10-34
HazardClass 
IRRITANT
HS Code 
29339900

MSDS

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1-Boc-4-(aminomethyl)piperidine Usage And Synthesis

Chemical Properties

White Low Melting Solid

Uses

1-Boc-4-(aminomethyl)piperidine is a protected 4-substituted piperidinecarboxylate used in the preparation of orally active platelet-activating factor antagonists as well as other biologically active compounds.

Uses

1-Boc-4-(aminomethyl)piperidine is used in the preparation biologically active compounds and orally active platelet-activating factor antagonists. It is used as an inhibitor for Kinesin spindle protein. It is an active reactant involved in the enantioselective synthesis of N-alkyl terminal aziridines.Precursor in the preparation of a variety of different protein agonists or antagonists including: Orphan G-protein coupled receptor GPR119 agonist with antidiabetic potential, Pim-1 inhibitors, and Aspartic acid protease inhibitors.

1-Boc-4-(aminomethyl)piperidine Preparation Products And Raw materials

Raw materials

EtanolSodium hydroxideEthyl acetateMethanolTetrahydrofuranDichloromethanePETROLEUM ETHERSodium carbonateTriethylamineLithium aluminium hydride1,4-DioxaneDi-tert-butyl dicarbonateBenzaldehydeTosyl chlorideSodium amide1,1'-CarbonyldiimidazoleIsonipecotic acid4-Methylmorpholine Sodium bisulfate4-Piperidinemethanol

1-Boc-4-(aminomethyl)piperidineSupplier

BTC Pharmaceutical CO. Ltd Gold
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INTATRADE GmbH
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+49 3493/605464
Email
sales@intatrade.de
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