3-PHENYL-1,1,1-TRIFLUOROPROPAN-2-ONE Chemical Properties

Boiling point:

51-52 °C2 mm Hg(lit.)

Density 

1.22 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.444(lit.)

Flash point:

91 °F

storage temp. 

Sealed in dry,Room Temperature

form 

liquid

color 

Clear, faint yellow

BRN 

2614467

CAS DataBase Reference

350-92-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,F

Risk Statements 

10

Safety Statements 

16

RIDADR 

UN 1224 3/PG 3

WGK Germany 

3

Hazard Note 

Flammable/Irritant

HazardClass 

IRRITANT

HS Code 

29147000

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

3-PHENYL-1,1,1-TRIFLUOROPROPAN-2-ONE Usage And Synthesis

Chemical Properties

clear colorless to light yellow liquid

Synthesis Reference(s)

Journal of Medicinal Chemistry, 42, p. 3315, 1999 DOI: 10.1021/jm980734a
Tetrahedron Letters, 28, p. 4259, 1987 DOI: 10.1016/S0040-4039(00)96479-7
The Journal of Organic Chemistry, 54, p. 661, 1989 DOI: 10.1021/jo00264a029

General Description

1,1,1-Trifluoro-3-phenyl-2-propanone is a trifluoromethyl ketone. Its in vitro neuroprotective potency against low K(+)-induced apoptosis in cerebellar granule neurons (CGNs) by different pathways has been reported.

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