AC-IEPD-AMC
AC-IEPD-AMC Basic information
- Product Name:
- AC-IEPD-AMC
- Synonyms:
-
- N-Acetyl-L-isoleucyl-L-alpha-glutamyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-alpha-asparagine
- GRANZYME B SUBSTRATE IX, FLUOROGENIC
- AC-IEPD-AMC
- AC-ILE-GLU-PRO-ASP-7-AMINO-4-METHYLCOUMARIN
- N-ACETYL-ILE-GLU-PRO-ASP-7-AMIDO-4-METHYLCOUMARIN
- AC-ILE-GLU-PRO-ASP-AMC
- L-α-Asparagine, N-acetyl-L-isoleucyl-L-α-glutamyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
- N-Acetyl-L-isoleucyl-L-α-glutamyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine
- CAS:
- 216757-33-4
- MF:
- C32H41N5O11
- MW:
- 671.69
- Product Categories:
-
- Pepetides
- Mol File:
- 216757-33-4.mol
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AC-IEPD-AMC Chemical Properties
- Boiling point:
- 1116.0±65.0 °C(Predicted)
- Density
- 1.366±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- DMSO/DMF: 1 mg/mL
- form
- powder
- pka
- 4.12±0.10(Predicted)
- Sequence
- Ac-Ile-Glu-Pro-Asp-{AMC}
MSDS
- Language:English Provider:SigmaAldrich
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AC-IEPD-AMC Usage And Synthesis
Uses
Ac-IEPD-AMC is a fluorogenic substrate for the determination of protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal[1].
References
[1] Scott JI, et, al. A Functional Chemiluminescent Probe for in Vivo Imaging of Natural Killer Cell Activity Against Tumours. Angew Chem Int Ed Engl. 2021 Mar 8;60(11):5699-5703. DOI:10.1002/anie.202011429
AC-IEPD-AMCSupplier
Shanghai Hanhong Scientific Co.,Ltd.
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
Chemsky (shanghai) International Co.,Ltd
- Tel
- 021-50135380
- shchemsky@sina.com
Cellmano Biotech Limited
- Tel
- 0551-65326643 18156095617
- info@cellmano.com
BOC Sciences
- Tel
- 1-631-485-4226; 16314854226
- info@bocsci.com
Nanjing Leon Biological Technology Co., Ltd.
- Tel
- 17705183659
- sales@njleonbiotech.com
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AC-IEPD-AMC(216757-33-4)Related Product Information
- GRANZYME B
- AC-ALA-ALA-PRO-ALA-AMC
- AC-IEPD-AFC
- AC-IEPD-AMC
- L-PYROGLUTAMYL-L-ARGINYL-L-THREONYL-L-LYSYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDE
- DABCYL-LYS-HCOV-SARS REPLICASE POLYPROTEIN 1AB (3235-3246)-GLU-EDANS
- MCA-SER-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-ARG-LYS(DNP)-ARG-ARG-NH2
- Ac-Val-Arg-Pro-Arg-AMC
- DABCYL-TYR-VAL-ALA-ASP-ALA-PRO-VAL-EDANS
- BENZYLOXYCARBONYL-L-VALYL-L-LYSYL-L-METHIONINE 4-METHYLCOUMARYL-7-AMIDE HYDROCHLORIDE
- PGLU-GLY-ARG P-NITROANILIDE HYDROCHLORID
- MCA-GLY-LYS-PRO-ILE-LEU-PHE-PHE-ARG-LEU-LYS(DNP)-D-ARG-NH2
- MCA-ARG-PRO-LYS-PRO-TYR-ALA-NVA-TRP-MET-LYS(DNP)-NH2
- SUC-ALA-ALA-ALA-AMC