2-BROMO-4-TERT-BUTYLPHENOL Chemical Properties

Melting point:

51°C(lit.)

Boiling point:

113°C/9mmHg(lit.)

Density 

1.341±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Oil

pka

8.65±0.18(Predicted)

color 

Clear Colourless

InChI

InChI=1S/C10H13BrO/c1-10(2,3)7-4-5-9(12)8(11)6-7/h4-6,12H,1-3H3

InChIKey

FFRLMQPMGIMHHQ-UHFFFAOYSA-N

SMILES

C1(O)=CC=C(C(C)(C)C)C=C1Br

Safety Information

Hazard Codes 

Xi

HazardClass 

IRRITANT

HS Code 

2908190090

2-BROMO-4-TERT-BUTYLPHENOL Usage And Synthesis

Chemical Properties

White crystalline

Uses

2-Bromo-4-tert-butylphenol is useful synthetic compound that can be used to prepare 2-?Mesityl-?4-?tert-?butylphenol.

Synthesis

A method for the preparation of 2-bromo-4-tert-butylphenol, comprising the steps of S11. dissolving 1 mol 4-tert-butylphenol in 300-500 ml of acetic acid solution at room temperature, followed by adding 150-250 ml of water, stirring well, and then adding 1.01 mol of sodium bromide; S12. slowly dropping in 10% sodium chlorite solution (effective chlorine content of 128.2.0 sodium bromide equivalents) over a period of 1-2 hours at room temperature and stirring; and continuing the reaction for 4-8 hours after dropping. Sodium solution (effective chlorine content of 128.2.0 sodium bromide equivalent), after dropping, continue to stir the reaction at room temperature for 4-8 hours. The conversion of 2-bromo-4-tert-butylphenol prepared by this method was more than 99%, the yield was 97% and the purity of the product was 98.3%.

References

[1] Journal of the American Chemical Society, 1982, vol. 104, # 5, p. 1362 - 1368
[2] Chemistry - A European Journal, 2012, vol. 18, # 11, p. 3286 - 3291
[3] Patent: US2014/135320, 2014, A1. Location in patent: Page/Page column 0219
[4] Patent: US2014/135360, 2014, A1. Location in patent: Paragraph 0147
[5] Tetrahedron Asymmetry, 1999, vol. 10, # 3, p. 411 - 427

2-BROMO-4-TERT-BUTYLPHENOL(2198-66-5)Related Product Information

• 2,6-dibromo-4-[1-(3-bromo-4-hydroxyphenyl)-1-methylethyl]phenol
• Tetrabromobisphenol A
• TETRABROMOBISPHENOL A DIGLYCIDYL ETHER
• 2,2',6,6'-Tetrabromobisphenol A diallyl ether
• 4,4'-Isopropylidenebis[2-(2,6-dibromophenoxy)ethanol]
• 2-BROMO-4-TERT-BUTYLPHENOL
• 2-BROMO-4,6-DI-TERT-BUTYLPHENOL
• Tetrabromobisphenol A bis(dibromopropyl ether)
• 4-tert-Butylphenol
• 4-(1-ADAMANTYL)-2-BROMOPHENOL
• CHEMBRDG-BB 5216515
• 2,6-DIBROMO-4-TERT-BUTYL-PHENOL
• 2,2',6,6'-TETRABROMO BISPHENOL ''A'' DIACRYLATE
• 2,2',6,6'-TETRABROMO BISPHENOL ''A'' DIMETHACRYLATE
• TETRABROMOBISPHENOL A DIMETHYL ETHER
• 4,5-DIBROMO-2,7-DI-TERT-BUTYL-9,9-DIMETHYLXANTHENE
• 5-BROMO-2-TERT-BUTYLPHENOL
• AURORA 21972