LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE Chemical Properties

Density 

1.45±0.1 g/cm3(Predicted)

storage temp. 

−20°C

form 

Powder

pka

3.56±0.10(Predicted)

Water Solubility 

Soluble to 1 mg/ml in water

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE Usage And Synthesis

Uses

[Lys-des-Arg9]-Bradykinin has been used as a B1R agonist to investigate the role of B1R in diabetes-induced secondary hemorrhage.

Biochem/physiol Actions

[Des-Arg10]-kallidin or [Lys-des-Arg9]-Bradykinin is a bradykinin B1 receptor agonist. It strongly upregulates the B1 receptor and is blocked by a specific protein kinase C inhibitor. The upregulation is correlated with the induction of transcription nuclear factor κB (NF-κB). Elevation of Lys-des[Arg9]–bradykinin because of airway inflammation in asthma patients is known to modify the immune responses. It affects the migration and production of interleukin-12 in monocyte-derived dendritic cells.

storage

Store at -20°C

LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE(71800-36-7)Related Product Information

• L(+)-Arginine
• L-Lysine
• GLY-PHE-SER
• LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG,H-LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG-OH
• MET-LYS-BRADYKININ
• H-LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG-SER-VAL-GLN-VAL-SER-OH
• LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG (HUMAN, BOVINE) 3ACOH 4H2O
• LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE 2ACOH 4H2O
• ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE
• PHE-GLY-GLY-PHE
• H-PRO-PHE-OH
• KALLIDIN, (DES-10-ARG) [3,4-PROLYL-3,4-3H(N)]-
• LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE