2-Chloro-5-nitrobenzoyl chloride Chemical Properties

Melting point:

58-60°C

Boiling point:

157-158°C 11mm

Density 

1.575±0.06 g/cm3(Predicted)

Flash point:

157-158°C/11mm

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

form 

powder to crystal

color 

White to Orange to Green

Sensitive 

Moisture Sensitive

BRN 

2213721

CAS DataBase Reference

25784-91-2(CAS DataBase Reference)

NIST Chemistry Reference

2-Chloro-5-nitrobenzoyl chloride(25784-91-2)

EPA Substance Registry System

Benzoyl chloride, 2-chloro-5-nitro- (25784-91-2)

Safety Information

Hazard Codes 

C,Xi

Risk Statements 

34-41

Safety Statements 

26-36/37/39-45

RIDADR 

3261

TSCA 

T

HS Code 

2916.39.7900

HazardClass 

8

PackingGroup 

II

MSDS

• Language:English Provider:2-Chloro-5-nitrobenzoyl chloride
• Language:English Provider:ALFA

2-Chloro-5-nitrobenzoyl chloride Usage And Synthesis

Biological Activity

2-Chloro-5-nitrobenzoyl chloride (2CNBCl) is an amide that contains a terminal alkyne. It is synthesized from the corresponding thionyl chloride and ethanolamine in the presence of carbon tetrachloride. 2CNBCl has been shown to inhibit the growth of various cancer cell lines, including those derived from melanoma, lung, breast, and colon cancer cells. 2CNBCl also inhibits the production of growth factor proteins such as platelet-derived growth factor (PDGF). 2CNBCl has also been shown to inhibit DNA synthesis by interacting with enzymes involved in the process.

2-Chloro-5-nitrobenzoyl chloride(25784-91-2)Related Product Information

• Calcium chloride
• Epichlorohydrin
• 4-Fluorobenzoyl chloride
• 2-Fluorobenzoyl chloride
• 2-Chlorobenzoyl chloride
• 3-Methylbenzoyl chloride
• 2,3,4,5-Tetrafluorobenzoyl chloride
• Benzoyl chloride
• p-Toluoyl chloride
• Sodium chloride
• o-Toluoyl chloride
• Polyvinyl chloride
• Choline chloride
• Ammonium chloride
• Methylene Chloride
• 3,5-Dinitrobenzoyl chloride
• 2-Nitrobenzoyl chloride
• Chloroacetic acid