Basic information Safety Supplier Related

Isonipecotic acid

Basic information Safety Supplier Related

Isonipecotic acid Basic information

Product Name:
Isonipecotic acid
Synonyms:
  • Isonipecotic acid, 4-Carboxypiperidine
  • 4 - piperidine forMic acid
  • Isonipecotic aci
  • Isonipecotic acid, 99% 25GR
  • Piperidin-4-carboxylic acid
  • 4-PIPERIDINECARBOXYLIC ACID FOR SYNTHESI
  • Piperidine-4-carboxylic acid or isonipecotic acid
  • AKOS BBS-00003783
CAS:
498-94-2
MF:
C6H11NO2
MW:
129.16
EINECS:
207-872-3
Product Categories:
  • Acids and Derivatives
  • Amines and Anilines
  • Nitrogen cyclic compounds
  • blocks
  • Carboxes
  • Heterocycles
  • Carboxylic Acids
  • Pyrans, Piperidines &Piperazines
  • Piperidine
  • Organic acids
  • Terfenadine Fexofenadine Ketanserin
  • Carboxylic Acids
  • Pyrans, Piperidines & Piperazines
Mol File:
498-94-2.mol
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Isonipecotic acid Chemical Properties

Melting point:
>300 °C(lit.)
Boiling point:
239.22°C (rough estimate)
Density 
1.1426 (rough estimate)
refractive index 
1.4587 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Water
form 
Powder
pka
pK1:3.73(+1);pK2:10.72(0) (25°C)
color 
White to faint pink-beige
Water Solubility 
soluble
Merck 
14,5189
BRN 
112553
CAS DataBase Reference
498-94-2(CAS DataBase Reference)
EPA Substance Registry System
4-Piperidinecarboxylic acid (498-94-2)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
NS5150000
TSCA 
T
HazardClass 
IRRITANT
HS Code 
29333999

MSDS

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Isonipecotic acid Usage And Synthesis

Chemical Properties

white to faint pink-beige powder

Uses

A GABA-A receptor partial agonist

Synthesis Reference(s)

Synthesis, p. 623, 1984
Tetrahedron Letters, 35, p. 8783, 1994 DOI: 10.1016/S0040-4039(00)78497-8

Purification Methods

It crystallises from H2O or EtOH as needles. The hydrochloride recrystallises from H2O or aqueous HCl with m 293odec (also 298odec, 300odec). [Wibaut Recl Trav Chim Pays-Bas 63 141 1944, IR: Zacharius et al. J Am Chem Soc 76 2908 1954, Beilstein 22/1 V 244.]

Isonipecotic acid Preparation Products And Raw materials

Preparation Products

4-BENZYLPIPERIDINE1-Boc-4-(aminomethyl)piperidine4-N-BOC-Aminopiperidine1-(PIPERIDIN-4-YLCARBONYL)PIPERIDINE4-CyanopiperidineBENZYL 4-(BROMOMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE1-ACETYL-4-BENZOYLPIPERIDINEPHENYL(PIPERIDIN-4-YL)METHANONE6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole4-(Boc-Aminomethyl)piperidine1-tert-Butoxycarbonyl-4-piperidinecarboxaldehydeN-BOC-ISONIPECOTIC ACID1-Methylpiperidin-4-amine1-(4-ACETYLPIPERIDINO)ETHAN-1-ONE1-Boc-4-cyanopiperidine1-METHYLPIPERIDINE-4-CARBOXYLIC ACID HYDROCHLORIDE1-ACETYLISONIPECOTOYL CHLORIDE1-METHYL-PIPERIDINE-4-CARBOXYLIC ACID1-Acetyl-4-piperidinecarboxylic acidN-BOC-piperidine-4-carboxylic acid1-[(Benzyloxy)carbonyl]piperidine-4-carboxylic acid4-PIPERIDINECARBOXYLIC ACID T-BUTYL ESTER HCL

Isonipecotic acidSupplier

JIANGYIN RUISHIPHARM CO.,LIMITED Gold
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0510-0510-66227179 18921203887
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sales@ruishipharm.com
Shanghai Taijilin Industrial Co., Ltd. Gold
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021-021-50630626 18964684208
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kate@tajilin.com
Terma Medicare India Pvt Ltd Gold
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021-52530655 18930806002
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yuli@semsstar.com
J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Email
market03@meryer.com
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