Isonipecotic acid
Isonipecotic acid Basic information
- Product Name:
- Isonipecotic acid
- Synonyms:
-
- Isonipecotic acid, 4-Carboxypiperidine
- 4 - piperidine forMic acid
- Isonipecotic aci
- Isonipecotic acid, 99% 25GR
- Piperidin-4-carboxylic acid
- 4-PIPERIDINECARBOXYLIC ACID FOR SYNTHESI
- Piperidine-4-carboxylic acid or isonipecotic acid
- AKOS BBS-00003783
- CAS:
- 498-94-2
- MF:
- C6H11NO2
- MW:
- 129.16
- EINECS:
- 207-872-3
- Product Categories:
-
- Acids and Derivatives
- Amines and Anilines
- Nitrogen cyclic compounds
- blocks
- Carboxes
- Heterocycles
- Carboxylic Acids
- Pyrans, Piperidines &Piperazines
- Piperidine
- Organic acids
- Terfenadine Fexofenadine Ketanserin
- Carboxylic Acids
- Pyrans, Piperidines & Piperazines
- Mol File:
- 498-94-2.mol
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Isonipecotic acid Chemical Properties
- Melting point:
- >300 °C(lit.)
- Boiling point:
- 239.22°C (rough estimate)
- Density
- 1.1426 (rough estimate)
- refractive index
- 1.4587 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Water
- form
- Powder
- pka
- pK1:3.73(+1);pK2:10.72(0) (25°C)
- color
- White to faint pink-beige
- Water Solubility
- soluble
- Merck
- 14,5189
- BRN
- 112553
- CAS DataBase Reference
- 498-94-2(CAS DataBase Reference)
- EPA Substance Registry System
- 4-Piperidinecarboxylic acid (498-94-2)
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Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- RTECS
- NS5150000
- TSCA
- T
- HazardClass
- IRRITANT
- HS Code
- 29333999
MSDS
- Language:English Provider:4-Piperidinecarboxylic acid
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
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Isonipecotic acid Usage And Synthesis
Chemical Properties
white to faint pink-beige powder
Uses
A GABA-A receptor partial agonist
Synthesis Reference(s)
Synthesis, p. 623, 1984
Tetrahedron Letters, 35, p. 8783, 1994 DOI: 10.1016/S0040-4039(00)78497-8
Purification Methods
It crystallises from H2O or EtOH as needles. The hydrochloride recrystallises from H2O or aqueous HCl with m 293odec (also 298odec, 300odec). [Wibaut Recl Trav Chim Pays-Bas 63 141 1944, IR: Zacharius et al. J Am Chem Soc 76 2908 1954, Beilstein 22/1 V 244.]
Isonipecotic acid Preparation Products And Raw materials
Preparation Products
4-BENZYLPIPERIDINE1-Boc-4-(aminomethyl)piperidine4-N-BOC-Aminopiperidine1-(PIPERIDIN-4-YLCARBONYL)PIPERIDINE4-CyanopiperidineBENZYL 4-(BROMOMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE1-ACETYL-4-BENZOYLPIPERIDINEPHENYL(PIPERIDIN-4-YL)METHANONE6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole4-(Boc-Aminomethyl)piperidine1-tert-Butoxycarbonyl-4-piperidinecarboxaldehydeN-BOC-ISONIPECOTIC ACID1-Methylpiperidin-4-amine1-(4-ACETYLPIPERIDINO)ETHAN-1-ONE1-Boc-4-cyanopiperidine1-METHYLPIPERIDINE-4-CARBOXYLIC ACID HYDROCHLORIDE1-ACETYLISONIPECOTOYL CHLORIDE1-METHYL-PIPERIDINE-4-CARBOXYLIC ACID1-Acetyl-4-piperidinecarboxylic acidN-BOC-piperidine-4-carboxylic acid1-[(Benzyloxy)carbonyl]piperidine-4-carboxylic acid4-PIPERIDINECARBOXYLIC ACID T-BUTYL ESTER HCL
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Isonipecotic acid(498-94-2)Related Product Information
- 2,2,6,6-Tetramethyl-4-piperidinol
- Citric acid
- Isonipecotic acid ethyl,ISONIPECOTIC ACID ETHYL ESTER
- Folic acid
- DROPERIDOL
- ISONIPECOTIC ACID, METHYL AND ETHYL ESTERS,Isonipecotic acid methyl
- Hyaluronic acid
- Triacetonediamine
- Haloperidol
- Ethyl 2-(Chlorosulfonyl)acetate
- Benzyl 4-hydroxy-1-piperidinecarboxylate
- Ascoric Acid
- Azido-PEG1-CH2CO2H
- 4-HYDROXY-3-METHYLBENZOIC ACID
- Hexahydroisonicotinamide
- 4-Pyrimidinecarboxylic acid
- 4,4-Piperidinediol hydrochloride
- PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER HYDROCHLORIDE