Basic information Safety Supplier Related

(S)-1,4-BENZODIOXAN-2-CARBOXYPIPERAZINE

Basic information Safety Supplier Related

(S)-1,4-BENZODIOXAN-2-CARBOXYPIPERAZINE Basic information

Product Name:
(S)-1,4-BENZODIOXAN-2-CARBOXYPIPERAZINE
Synonyms:
  • (S)-(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)(piperazin-1-yl)methanone
  • REF DUPL: (S)-1,4-Benzodioxan-2-carboxypiperazine
  • Methanone, [(2S)-2,3-dihydro-1,4-benzodioxin-2-yl]-1-piperazinyl-
  • (S)-1,4-BENZODIOXAN-2-CARBOXYPIPERAZINE
  • (S)-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-2-YL)-PIPERAZIN-1-YL-METHANONE
  • (S)-N-(1,4-benzodioxan-2-carbonyl)piperazine
CAS:
401941-54-6
MF:
C13H16N2O3
MW:
248.28
Mol File:
401941-54-6.mol
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(S)-1,4-BENZODIOXAN-2-CARBOXYPIPERAZINE Chemical Properties

Melting point:
129-132oC
Boiling point:
437.2±45.0 °C(Predicted)
Density 
1.246±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
8.32±0.10(Predicted)
form 
Solid
color 
White
CAS DataBase Reference
401941-54-6(CAS DataBase Reference)
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(S)-1,4-BENZODIOXAN-2-CARBOXYPIPERAZINE Usage And Synthesis

Uses

(S)-1,4-Benzodioxan-2-carboxypiperazine is the key chiral intermediate for the synthesis of (S)-doxazosin (D537500, Mesylate salt), a selective α1-adrenoceptor antagonist. Doxazosin relaxes smooth muscles of the prostate.

(S)-1,4-BENZODIOXAN-2-CARBOXYPIPERAZINESupplier

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