2-Pyridinecarbaldehyde oxime Chemical Properties

Melting point:

110-112 °C(lit.)

Boiling point:

227.52°C (rough estimate)

Density 

1.2236 (rough estimate)

vapor pressure 

0.02-0.041Pa at 20-25℃

refractive index 

1.4738 (estimate)

storage temp. 

Store below +30°C.

solubility 

methanol: 0.1 g/mL, clear

form 

Solid

pka

pK1: 3.42(+1);pK2: 10.22(0) (25°C)

color 

Off-White

Water Solubility 

15 g/L (20 ºC)

BRN 

109061

LogP

0.3 at 25℃

CAS DataBase Reference

873-69-8(CAS DataBase Reference)

NIST Chemistry Reference

2-Pyridinealdoxime(873-69-8)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

22-37/38-41-36/37/38-20/22

Safety Statements 

26-36/37/39-37/39

WGK Germany 

3

RTECS 

TJ4180000

Hazard Note 

Irritant

HS Code 

29333999

Toxicity

LD50 intraperitoneal in mouse: 200mg/kg

MSDS

• Language:English Provider:2-Pyridinecarbaldehyde oxime
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2-Pyridinecarbaldehyde oxime Usage And Synthesis

Chemical Properties

White powder

Uses

syn-2-Pyridinealdoxime is a 2-substituted pyridine derivative with inhibitory activity against prolyl-4-hydroxylase. syn-2-Pyridinealdoxime is used in the preparation of DNA-binding silver nitrate complexes. syn-2-Pyridinealdoximeis the N-demethylated analogue of AChE inhibitor Pralidoxime (P701120).

Purification Methods

Recrystallise it from Et2O/pet ether or H2O. The picrate has m 169-171o (from aqueous EtOH). It is used in peptide synthesis. [UV: Grammaticakis Bull Chem Soc Fr 109, 116 1956, Ginsberg & Wilson J Am Chem Soc 79 481 1957, Hanania & Irvine Nature 183 40 1959, Green & Saville J Chem Soc 3887 1956, Beilstein E-isomer 21 I 288, 21 III/IV 3504, 21/7 V 305.]

2-Pyridinecarbaldehyde oxime(873-69-8)Related Product Information

• 4-Pyridinecarboxaldehyde
• Sulfasalazine
• 3-Pyridinecarboxaldehyde
• Chromium picolinate
• 2-Hydroxypyridine
• 2-Pyridinecarboxaldehyde
• 2,6-Lutidine
• FORMOXIME
• Pyridine hydrochloride
• 2,6-Pyridinedicarbonitrile
• 4-Pyridinesulfonamide(6CI,9CI)
• 2,3,5,6-Tetraaminopyridine trihydrochloride
• Pyridine trifluoroacetate
• PYRIDINE-2-THIOAMIDE
• 2-Pyridinesulfonamide(6CI,7CI,9CI)
• dimethyl pyridine-3,5-dicarboxylate
• METHYL ISONICOTINATE
• Pyridine-N-oxide