1-METHYLHISTAMINE DIHYDROCHLORIDE Chemical Properties

Melting point:

>198°C (dec.)

storage temp. 

2-8°C

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

powder

color 

Pale Yellow

Stability:

Hygroscopic

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

2933299090

MSDS

• Language:English Provider:SigmaAldrich

1-METHYLHISTAMINE DIHYDROCHLORIDE Usage And Synthesis

Description

1-Methylhistamine is a major metabolite of histamine by histamine N-methyltransferase in the pathway of histidine metabolism. It has been used as a biomarker of histaminergic system activity in the brains of Alzheimer’s disease patients as well as those with hypersomnia and other neurological conditions.

Uses

1-Methylhistamine Dihydrochloride is a selective H1-receptor agonists. Also it has depressant effects.

Biochem/physiol Actions

Major metabolite of histamine by histamine N-methyltransferase.

1-METHYLHISTAMINE DIHYDROCHLORIDE(6481-48-7)Related Product Information

• Histamine
• Histamine dihydrochloride
• N'-Methyl-L-histidine methyl ester
• (S)-4,5,6,7-Tetrahydro-3-phenylmethyl-3H-imidazo[4,5-c]pyridine-6-carboxylic acid dihydrochloride
• H-HIS(BZL)-OME 2 HCL
• 1-METHYLHISTAMINE DIHYDROCHLORIDE
• 2-AMINO-1-[5-AMINO-1-(PHENYLMETHYL)-1H-IMIDAZOL-4-YL] ETHANONE
• N-TAU-METHYL-D3-HISTAMINE 2HCL
• n-Methylhistamine dihydrochloride
• 2-Methylhistamine dihydrochloride
• S(+)-α-Methylhistamine dihydrochloride
• 3-METHYLHISTAMINE DIHYDROCHLORIDE
• β-Methylhistamine dihydrochloride
• (S)-2-AMINO-3-(1-METHYL-1H-IMIDAZOL-4-YL)-PROPIONIC ACID 2HCL
• R(-)-ALPHA-METHYLHISTAMINE DIHYDROCHLORIDE,(R)-(-)-A-methylhistamine*dihydrochloride,(r)(-)-α-methylhistamine dihydrochloride
• 4-Methylhistamine dihydrochloride
• N-ALPHA-METHYLHISTAMINE DIHYDROCHLORIDE,NA-METHYLHISTAMINE DIHYDROCHLORIDE,Methylhistamine dihydrochloride Nalpha-
• METHYLHISTAMINE DIHYDROCHLORIDE, N-ALPHA-[METHYL-3H]-