Basic information Safety Supplier Related

PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2

Basic information Safety Supplier Related

PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2 Basic information

Product Name:
PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2
Synonyms:
  • (d-ala(sup6))-lhrh
  • (d-ala(sup6))-luteinizinghormone-releasinghormon
  • (d-ala(sup6))-luteinizinghormone-releasinghormone
  • wy-18186
  • (D-ALA6)-GONADOTROPIN-RELEASING HORMONE
  • (D-ALA6)-LHRH
  • PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2
  • PYROGLU-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY NH2
CAS:
51230-19-4
MF:
C56H77N17O13
MW:
1196.32
Mol File:
51230-19-4.mol
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PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2 Chemical Properties

Density 
1.52±0.1 g/cm3(Predicted)
storage temp. 
−20°C
pka
9.82±0.15(Predicted)
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Safety Information

Hazard Codes 
T
Risk Statements 
60
Safety Statements 
53-22-36/37/39-45
WGK Germany 
3
RTECS 
OK6400000
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PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2 Usage And Synthesis

Uses

[D-Ala6]-LH-RH acetate salt hydrate has been used to induce ovulation and to synchronize the reproductive cycle in Sprague-Dawley female rats.

Biochem/physiol Actions

(D-Ala6)-LH-RH is a GnRH (gonadotropin-releasing hormone) agonist. GnRH, which is also referred to as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism.

PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2Supplier

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