4-Fluoro-3-nitrotoluene Chemical Properties

Melting point:

28 °C

Boiling point:

241 °C

Density 

1.262

refractive index 

1.524

Flash point:

22 °C

storage temp. 

Sealed in dry,Room Temperature

form 

Liquid

Specific Gravity

1.262

color 

Red-brown

CAS DataBase Reference

446-11-7(CAS DataBase Reference)

NIST Chemistry Reference

4-Fluoro-3-nitrotoluene(446-11-7)

Safety Information

Hazard Codes 

Xi,C

Risk Statements 

20/21/22-36/37/38-34

Safety Statements 

26-36-45-36/37/39

Hazard Note 

Irritant

HazardClass 

6.1

HS Code 

2904990090

4-Fluoro-3-nitrotoluene Usage And Synthesis

Description

The molecular structure of 4-fluoro-3-nitrotoluene contains four functional groups: benzene ring, fluorine atom, nitro group and methyl group. Among them, the benzene ring is the basic structural unit of aromatic compounds, the fluorine atom has a strong electron-withdrawing property, the nitro group is a strong electron-withdrawing group, and the methyl group is an electron-donating group. 4-fluoro-3-nitrotoluene has a wide range of applications in organic synthesis, mainly as a pharmaceutical and pesticide intermediate. For example, it can be used to synthesize a variety of drugs, such as cardiovascular drugs, anti-inflammatory drugs, antibiotics, etc. In pesticides, 4-fluoro-3-nitrotoluene can prepare herbicides, fungicides, insecticides, etc. In addition, 4-fluoro-3-nitrotoluene can also be used as an intermediate in synthetic dyes, plastics, synthetic fibers, etc. In analytical chemistry, it can be used as a standard solution for titration analysis, calibration of instruments and devices, evaluation methods, working standards, quality assurance/quality control, etc.

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