2-Amino-2-methyl-1,3-propanediol Chemical Properties

Melting point:

100-110 °C (lit.)

Boiling point:

151 °C/10 mmHg (lit.)

Density 

1.0509 (estimate)

vapor density 

3.63 (vs air)

vapor pressure 

~10 mm Hg ( 152 °C)

refractive index 

1.4754 (estimate)

Flash point:

>100°C

storage temp. 

Store below +30°C.

solubility 

H₂O: 1 M at 20 °C, clear, colorless

form 

Crystalline Powder

color 

White

PH

10.0-12.0 (20℃, 0.5M in H2O)

pka

8.8(at 25℃)

PH Range

7.8 - 9.7

Water Solubility 

2500 g/L (20 ºC)

λmax

λ: 260 nm Amax: 0.05
λ: 280 nm Amax: 0.03

Merck 

13,447

BRN 

635708

Stability:

Stable. Combustible. May be moisture-sensitive. Incompatible with strong oxidizing agents, copper, aluminium, brass, strong acids.

LogP

-1.31 at 22℃

CAS DataBase Reference

115-69-5(CAS DataBase Reference)

NIST Chemistry Reference

2-Amino-2-methyl-1,3-propanediol(115-69-5)

EPA Substance Registry System

1,3-Propanediol, 2-amino-2-methyl- (115-69-5)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-20/21/22

Safety Statements 

26-36-37/39

RIDADR 

UN 3259 8/PG 2

WGK Germany 

1

RTECS 

TY2975000

F 

3-23

TSCA 

Yes

PackingGroup 

III

HS Code 

29221980

Toxicity

LD50 orally in Rabbit: 17000 mg/kg

MSDS

• Language:English Provider:AMPD
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

2-Amino-2-methyl-1,3-propanediol Usage And Synthesis

Chemical Properties

white powder

Uses

Emulsifying agent (in soap form) for oils, fats, and waxes; absorbent for acidic gases; organic synthesis; cosmetics.

Uses

A useful biological buffer2-Amino-2-methyl-1,3-propanediol is used to make surfactants, vulcanization accelerators and as a biological buffer. It acts as an absorbent for acidic gases and emulsifying agent for cosmetics, mineral oil, leather dressings, textile specialties and cleaning compounds. It is also used in hair sprays. It acts as a buffer for the determination of alkaline phosphatase activity and spacer in isotachophoresis of proteins. It serves as a reaction buffer for enzymes with an activity in the basic pH range such as alkaline phosphatase. Further, it is used in the preparation of 4-hydroxymethyl-4-methyl-oxazolidin-2-one.

Definition

ChEBI: An aminodiol that is propane-1,3-diol substituted ny an amino and a methyl group at position 2.

Purification Methods

Crystallise the diol three times from MeOH, dry in a stream of dry N2 at room temperature, then in a vacuum oven at 55o. Store it over CaCl2 [Hetzer & Bates J Phys Chem 66 308 1962]. [Beilstein 4 IV 1881.]

2-Amino-2-methyl-1,3-propanediol(115-69-5)Related Product Information

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