Mobocertinib
Mobocertinib Basic information
- Product Name:
- Mobocertinib
- Synonyms:
-
- TAK-788
- AP32788, MOBOCERTINIB
- Mobocertinib
- 5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-[(1-oxo-2-propen-1-yl)amino]phenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester
- Mobocertinib (TAK788)
- Isopropyl 2-((5-acrylamido-4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxyphenyl)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate
- Mobocertinib (TAK788, AP32788)
- propan-2-yl 2-[4-[2-(dimethylamino)ethyl-methylamino]-2-methoxy-5-(prop-2-enoylamino)anilino]-4-(1-methylindol-3-yl)pyrimidine-5-carboxylate
- CAS:
- 1847461-43-1
- MF:
- C32H39N7O4
- MW:
- 585.71
- Product Categories:
-
- API
- Mol File:
- 1847461-43-1.mol
More
Less
Mobocertinib Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- DMF: 10 mg/ml,DMF:PBS (pH 7.2) (1:8): 0.11 mg/ml
- form
- A crystalline solid
More
Less
Mobocertinib Usage And Synthesis
Uses
Mobocertinib (TAK-788) is an orally active and irreversible EGFR/HER2 inhibitor. Mobocertinib effectively inhibits oncogenic variants containing mutations that activate the EGFRex20ins, with selectivity superior to that of wild-type EGFR. Mobocertinib is FDA-approved for the treatment of patients with non-small cell lung cancer (NSCLC) who have a HER2 mutation or an EGFR mutation, including an exon 20 insertion mutation. Mobocertinib is approved by the FDA for the treatment of patients with non-small cell lung cancer (NSCLC) who have HER2 mutations or EGFR mutations, including exon 20 insertion mutations.
MobocertinibSupplier
Jinan shenlikang chemical technology co. LTD Gold
- Tel
- 0531-86092839 13153040268
- 2425815073@qq.com
Shanghai YuanQi Biotechnology Co., Ltd. Gold
- Tel
- +86-2332782371 +86-18120098618
- sales@adobechem.com
Jinan Chuanbei Biotechnology Co., Ltd Gold
- Tel
- 15269175648
- qingyan7590@163.com
Shanghai tingchong biology science and technology co., ltd Gold
- Tel
- 18964309092 18964309092
- 2769493375@qq.com
Changzhou Borl Biotechnology Co.,LTD Gold
- Tel
- 13606124132;13656121842
- luyan0021@163.com