4-Methylsulfonylaniline Chemical Properties

Melting point:

243-245°C

Boiling point:

384.3±34.0 °C(Predicted)

Density 

1.44

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly, Sonicated), Ethyl Acetate (Slightly, Sonicated)

form 

Crystalline Powder

pka

pK1:1.48(+1) (25°C)

color 

White

Water Solubility 

Soluble in water.

Sensitive 

Light Sensitive

CAS DataBase Reference

5470-49-5(CAS DataBase Reference)

NIST Chemistry Reference

4-Aminophenyl methyl sufhone(5470-49-5)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-22

Safety Statements 

22-24/25

Hazard Note 

Irritant

HazardClass 

6.1

HS Code 

2930909899

MSDS

• Language:English Provider:4-Mesylaniline

4-Methylsulfonylaniline Usage And Synthesis

Uses

It is used as pharmaceutical intermediate. A series of 4-(methylsulfonyl)aniline derivatives were synthesized in order to obtain new compounds as a potential anti-inflammatory agents with expected selectivity against COX-2 enzyme.

Synthesis Reference(s)

Tetrahedron Letters, 35, p. 7867, 1994 DOI: 10.1016/0040-4039(94)80139-8

4-Methylsulfonylaniline(5470-49-5)Related Product Information

• p-Toluidine
• o-Toluidine
• 4-(Trifluoromethoxy)aniline
• O-Tolidine
• 3,3'-Dimethylbenzidine dihydrochloride
• Pigment Red 3
• m-Toluidine
• p-Anisidine
• 2-AMINO-5-(4-NITROPHENYLSULFONYL)THIAZOLE
• 4'-(METHYLSULFONYL)ACETANILIDE
• REACTIVE BLACK 5
• [4-(Methylsulfonyl)phenyl]hydrazine hydrochloride
• 4-HEXADECYLSULFONYLANILINE
• REACTIVE ORANGE 16
• BIS(4-NITROPHENYL) SULFONE
• 4,4'-Diaminodiphenylsulfone
• N-Phenylmethanesulfonamide
• N-Phenyl-bis(trifluoromethanesulfonimide)