β-Amyloid (1-9) Chemical Properties

Density 

1.60±0.1 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

Soluble in DMSO

pka

3.21±0.10(Predicted)

Sequence

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly

β-Amyloid (1-9) Usage And Synthesis

Uses

β-Amyloid (1-9), an N-terminal fragment of beta amyloid, consists of amino acid residues 1 to 9. β-Amyloid (1-9) contains a B cell epitope, but it does not include T cell epitopes. Omission of residues 1 to 9 from the full-length Alzheimer'sβ-Amyloid peptide 1 to 40 does not prevent the peptide from forming amyloid fibrils or eliminate fibril polymorphism [1][2].

References

[1] Zamora E, et al. Papillomavirus-like particles are an effective platform for amyloid-beta immunization in rabbitsand transgenic mice. J Immunol. 2006 Aug 15;177(4):2662-2670. DOI:10.4049/jimmunol.177.4.2662
[2] Paravastu AK, et al. Polymorphic fibril formation by residues 10-40 of the Alzheimer's beta-amyloid peptide. Biophys J. 2006 Jun 15;90(12):4618-29. DOI:10.1529/biophysj.105.076927

β-Amyloid (1-9)(147529-30-4)Related Product Information

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