Basic information Safety Supplier Related

1-[3-(3,4-METHYLENEDIOXYPHENOXY)PROPYL]-4-PHENYL-PIPERAZINE MALEATE

Basic information Safety Supplier Related

1-[3-(3,4-METHYLENEDIOXYPHENOXY)PROPYL]-4-PHENYL-PIPERAZINE MALEATE Basic information

Product Name:
1-[3-(3,4-METHYLENEDIOXYPHENOXY)PROPYL]-4-PHENYL-PIPERAZINE MALEATE
Synonyms:
  • BP 554 MALEATE
  • 1-[3-(3,4-METHYLENEDIOXYPHENOXY)PROPYL]-4-PHENYL-PIPERAZINE MALEATE
  • BP 554
  • 1-[3-[(1,3-Benzodioxol-5-yl)oxy]propyl]-4-phenylpiperazine
  • 1-(3-(Benzo[d][1,3]dioxol-5-yloxy)propyl)-4-phenylpiperazine
  • Piperazine, 1-[3-(1,3-benzodioxol-5-yloxy)propyl]-4-phenyl-
CAS:
82900-57-0
MF:
C20H24N2O3
MW:
340.42
Mol File:
82900-57-0.mol
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1-[3-(3,4-METHYLENEDIOXYPHENOXY)PROPYL]-4-PHENYL-PIPERAZINE MALEATE Chemical Properties

Boiling point:
496.9±45.0 °C(Predicted)
Density 
1.188±0.06 g/cm3(Predicted)
storage temp. 
Store at RT
solubility 
<45.65mg/ml in DMSO
form 
solid
pka
7.42±0.10(Predicted)
color 
Off-white
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1-[3-(3,4-METHYLENEDIOXYPHENOXY)PROPYL]-4-PHENYL-PIPERAZINE MALEATE Usage And Synthesis

Uses

BP 554 Maleate was used to study the methods for the classification and diagnosis of scoliosis.

Definition

ChEBI: 1-[3-(1,3-benzodioxol-5-yloxy)propyl]-4-phenylpiperazine is a member of piperazines.

Biological Activity

Selective 5-HT 1A agonist.

References

[1]. matsuda t, seong yh, aono h, et al. agonist activity of a novel compound, 1-[3-(3,4-methylenedioxyphenoxy)propyl]-4-phenyl piperazine (bp-554), at central 5-ht1a receptors. eur j pharmacol, 1989, 170(1-2): 75-82.
[2]. galter d, unsicker k. sequential activation of the 5-ht1(a) serotonin receptor and trkb induces the serotonergic neuronal phenotype. mol cell neurosci, 2000, 15(5): 446-455.
[3]. rauch a, rainer g, logothetis nk. the effect of a serotonin-induced dissociation between spiking and perisynaptic activity on bold functional mri. proc natl acad sci u s a, 2008, 105(18): 6759-6764.

1-[3-(3,4-METHYLENEDIOXYPHENOXY)PROPYL]-4-PHENYL-PIPERAZINE MALEATESupplier

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