Bromodiphenylmethane Chemical Properties

Melting point:

35-39 °C(lit.)

Boiling point:

184 °C20 mm Hg(lit.)

Density 

0,9 g/cm³

refractive index 

1.6290 (estimate)

Flash point:

>230 °F

storage temp. 

Store below +30°C.

solubility 

0.45g/l

form 

powder to lump to clear liquid

color 

White to cream to yellow to orange to brown crystals or fused solid

PH

2 (H2O, 20℃)(saturated aqueous solution)

Water Solubility 

Insoluble

Sensitive 

Moisture Sensitive

BRN 

638544

CAS DataBase Reference

776-74-9(CAS DataBase Reference)

NIST Chemistry Reference

Benzene, 1,1'-(bromomethylene)bis-(776-74-9)

EPA Substance Registry System

Benzene, 1,1'-(bromomethylene)bis- (776-74-9)

Safety Information

Hazard Codes 

C

Risk Statements 

34-37

Safety Statements 

26-36/37/39-45

RIDADR 

UN 1770 8/PG 2

WGK Germany 

3

RTECS 

PA5350000

F 

19-21

TSCA 

Yes

HazardClass 

8

PackingGroup 

II

HS Code 

29036990

MSDS

• Language:English Provider:Diphenylbromomethane
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Bromodiphenylmethane Usage And Synthesis

Uses

Benzhydryl Bromide is used as a reagent in the synthesis of O-(triazolyl)methyl carbamates as a novel and potent class of fatty acid amide hydrolase (FAAH) inhibitors.

Chemical Properties

ORANGE-RED TO ORANGE-BROWN LOW MELTING SOLID

Uses

Benzhydryl bromide is a halogenated building block. Benzhydryl group was preferred to the commoner benzyl to protect 2-nitrophenol in the Bartoli (vinyl Grignard) synthesis of 7-hydroxyindole. Protection was by reaction with the phenol in the presence of potassium carbonate in acetone; deprotection of the indole was by hydrogenolysis.

General Description

Bromodiphenylmethane is a white crystalline solid. Melting point 113°F. A lachrymator. In the presence of moisture corrosive to tissue and most metals.

Air & Water Reactions

Insoluble in cold water. Decomposed by hot water to give corrosive hydrobromic acid.

Reactivity Profile

Halogenated aliphatic compounds are moderately or very reactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Materials in this group are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.

Safety Profile

A corrosive, irritating liquid, When heated to decomposition it emits toxic fumes of Br-. See also

Bromodiphenylmethane(776-74-9)Related Product Information

• 1,5-Diphenylcarbazide
• Diphenyldimethoxysilane
• Sodium bromate
• Chlorodiphenylphosphine
• Clidinium bromide
• Dibromomethane
• Dichlorodiphenylsilane
• Ethidium bromide
• 1,3-Diphenyl-2-thiourea
• CHLORODIBROMOMETHANE
• Diphenyldiazomethane
• BROMOTRIFLUOROMETHANE
• Triphenylmethyl bromide
• 4,4',4''-TRIS(4,5-DICHLOROPHTHALIMIDO)TRITYL BROMIDE
• 4,4',4''-TRIS(BENZOYLOXY)TRITYL BROMIDE
• 9-BROMOFLUORENE
• 2-BROMODIPHENYLMETHANE
• 9-Bromo-9-phenylfluorene