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De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride

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De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride Basic information

Product Name:
De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride
Synonyms:
  • De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride
  • 2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)acetic acid dihydrochloride
  • Cetirizine-3
  • Cetirizine EP Impurity B DiHCl (Levocetirizine Impurity 3 DiHCl)
  • Levocetirizine Impurity 3 DiHCl (Cetirizine EP Impurity B DiHCl)
  • Cetirizine Impurity B DiHCl
  • Cetirizine EP Impurity B DiHCl
  • Cetirizine Impurity B dihydrochloride
CAS:
1000690-91-4
MF:
C19H22Cl2N2O2
MW:
381.3
Mol File:
1000690-91-4.mol
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De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride Chemical Properties

Melting point:
>168°C (dec.)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form 
Solid
color 
White to Pale Beige
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De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride Usage And Synthesis

Uses

De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride, is an impurity of Cetirizine (C281100, 2HCl); a nonsedating type histamine H1-receptor antagonist and a major metabolite of Hydroxyzine (H996500). Pharmacological activity of Cetirizine resides primarily in the (R)-isomer. Also antihystaminic.

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