Cetirizine impurity B 2HCl Chemical Properties

Melting point:

>168°C (dec.)

storage temp. 

Hygroscopic, -20°C Freezer, Under inert atmosphere

solubility 

DMSO (Slightly), Methanol (Slightly), Water (Slightly)

form 

Solid

color 

White to Pale Beige

Cetirizine impurity B 2HCl Usage And Synthesis

Uses

De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride, is an impurity of Cetirizine (C281100, 2HCl); a nonsedating type histamine H1-receptor antagonist and a major metabolite of Hydroxyzine (H996500). Pharmacological activity of Cetirizine resides primarily in the (R)-isomer. Also antihystaminic.

Cetirizine impurity B 2HCl(1000690-91-4)Related Product Information

• Cetirizine dihydrochloride
• 3-Chlorobenzophenone
• Cetirizine Methyl Ester
• Cetirizine EP Impurity F
• Cetirizine Polyethylene Glycol (PEG) Ester
• 4-Chlorobenzophenone
• Cetirizine Related Compound C
• (2-CHLORO-PHENYL)-PHENYL-AMINE
• Cetirizine EP Impurity B(base)
• 1,4-BIS[(4-CHLOROPHENYL)PHENYLMETHYL]PIPERAZINE DIHYDROCHLORIDE
• rac Cetirizine N-Oxide > 70% by HPLC (Mixture of Diastereomers)
• 2(2-HYDROXYETHOXY)ACETAMIDE
• Cetirizine EP Impurity E
• Cetirizine Glycerol Ester
• Cetirizine Ethyl Ester (USP RC A)
• (RS)-2-[2-[4-[(2-Chloro-phenyl)phenylMethyl]piperazin-1-yl]ethoxy]aceticAcidDihydrochloride
• Levocetetrizine N-Oxide
• N-(2,4-Dichlorophenyl)benzenamine